Trial · NCT00773812
Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders
NCT00773812, Phase 1, Completed, Ohio State University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders. Trials, record NCT00773812. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00773812
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders
- NCT number
- NCT00773812
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 20 participants, actual
- Lead sponsor
- Ohio State University
- Conditions
- Autistic Disorder, Pervasive Developmental Disorder
- Interventions
- mecamylamine, placebo
- First posted
- 2008-10-16
- Last updated
- 2017-01-13
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The primary measure will be a global composite derived by calculating the z scores on each measure other than CGI from published norms (or from the baseline descriptives, then averaging the z scores of the various outcome measures for each individual. | Baseline, weeks 2, 4, 6, 8, 10,12, and 14. | |
| Secondary | OSU Autism Rating Scale-DSM-IV | Baseline, week 6, 8, and 14. | |
| Secondary | Repetitive Behavior Questionnaire | Baseline, week 2, 4, 6, 8, 10, 12, and 14 | |
| Secondary | Aberrant Behavior Checklist | Baseline, week 2, 4, 6, 8, 10, 12, and 14. | |
| Secondary | Ohio Autism Clinical Impressions Scale | Baseline, weeks 1, 2, 4, 6, 7, 8, 9, 10, 12, and 14. | |
| Secondary | Social Responsiveness Scale | Baseline, weeks 2, 4, 6, 8, 10, 12, and 14. | |
| Secondary | Expressive Vocabulary test-Second Edition | Baseline and week 14 | |
| Secondary | Adverse Experience checklist and AE log | Baseline, weeks 1, 2, 4, 6, 7, 8, 9, 10, 12, and 14. | |
| Secondary | Cognitive Battery | baseline, weeks 6, 8, and 14 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00773812
GET https://conductscience.org/api/trials/v1/NCT00773812/registered