Trial · NCT00777985
Preventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep Apnea
NCT00777985, Phase 2, Completed, University Hospital, Grenoble
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Preventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep Apnea. Trials, record NCT00777985. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00777985
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Preventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep Apnea
- NCT number
- NCT00777985
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 19 participants, actual
- Lead sponsor
- University Hospital, Grenoble
- Conditions
- Obstructive Sleep Apnea, Hypertension
- Interventions
- bosentan, nasal continuous positive airway pressure (CPAP)
- First posted
- 2008-10-23
- Last updated
- 2025-12-22
- Other registries' IDs
- eudract:2007-005333-11
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 24 hour mean diastolic blood pressure | before and after each treatment completion (4 weeks) | |
| Secondary | Peripheral Arterial Tonometry measure | before and after each treatment completion (4 weeks) | |
| Secondary | mean 24 hour systemic systolic blood pressure | before and after each treatment completion (4 weeks) | |
| Secondary | mean 24 hour nocturnal blood pressure | before and after each treatment completion (4 weeks) | |
| Secondary | carotid Intima Media Thickness | before and after each treatment completion (4 weeks) | |
| Secondary | Circulating inflammation markers (RANTES, MCP-1, TNF-alpha, INF-gamma, IL-6, IL-10 and TGF-gamma | before and after each treatment completion (4 weeks) | |
| Secondary | Circulating Big ET1 and ET1 levels | before and after each treatment completion (4 weeks) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 26643404 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00777985
GET https://conductscience.org/api/trials/v1/NCT00777985/registered