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Trial · NCT00799773

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryRole of Rituximab in Increasing Early Treatment Response in Participants With TTP Who Are Also Treated With Plasma Exchange and CorticosteroidsMeasured at Day 52
SecondaryUse of Non-study TreatmentMeasured at Month 36
SecondaryWhether Participants Receiving Rituximab Achieve Early or Late Treatment Response Faster and Require Fewer Plasma Exchanges Than Participants Not Receiving RituximabMeasured at Days 52 and 82
SecondaryRelationship Between Clinical and Laboratory Data and Response to TreatmentMeasured at Days 52 and 82
SecondaryIncidence of Relapse Among Participants in the Two Study Groups Who Achieve Early Treatment ResponseMeasured at Month 36
SecondaryAll Cause MortalityMeasured at Month 36
SecondaryTreatment-related ComplicationsMeasured at Day 52
Secondary
Evaluating How Levels of ADAMTS-13 Enzyme and Autoantibody at Specific Time Points or Over the Course of the Study Correlate With Other Indicators of Disease Activity, Remission Rates, Rapidity of Achieving a Remission, and Recurrence Rate
Measured at Month 36
SecondaryRituximab Response in Participants With Varying Levels of ADAMTS-13 Activity and Antibodies Against ADAMTS-13Measured at Month 36
SecondaryEffect of Plasma Exchange on Rituximab LevelsMeasured at Month 6
SecondaryEffect of Rituximab Levels on the Extent of B-cell Depletion (CD-19+ Cells)Measured at Month 12
SecondaryB-cell Depletion in Relation to ADAMTS-13 Activity and to ADAMTS-13 Antibody Levels and Disease Activity in Participants Who Receive Rituximab Versus Those Who do NotMeasured at Month 12

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT00799773/registered