Trial · NCT00812877
Pulp Capping With Two Different Agents
NCT00812877, Not applicable, Completed, Oregon Health and Science University; results first posted 2015-05-25
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pulp Capping With Two Different Agents. Trials, record NCT00812877. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00812877
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pulp Capping With Two Different Agents
- NCT number
- NCT00812877
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 376 participants, actual
- Lead sponsor
- Oregon Health and Science University
- Conditions
- Dental Pulp Exposure
- Interventions
- Mineral Trioxide Aggregate, Calcium Hydroxide
- First posted
- 2008-12-22
- Last updated
- 2015-05-25
- Results first posted
- 2015-05-25
- Limitations and caveats
1. Randomization was by practice therefore, some dentists may have used a material with which they had little familiarity.~2. Lack of on-going monitoring of study procedures may have caused an inordinate number of failures in one practice.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Tooth Survival | Up to two years | No recommendation for tooth extraction or root canal therapy. Only one tooth was enrolled/assessed per participant. |
| Secondary | Pulp Vitality | Up to two years | No evidence of pulpal resorption or calcification or periradicular radiolucency |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Tooth Survival | Up to two years | 12 subjects were excluded in the Mineral Trioxide Aggregate group due to lack of follow-up (4 subjects were non-responsive; unable to contact 6 subjects; 2 subjects changed dentists) and 6 subjects were in the Calcium Hydroxide group (2 subjects were non-responsive; unable to contact 3 subjects; 1 subject was incarcerated). | participants | NUMBER |
| SECONDARY | Pulp Vitality | Up to two years | participants | NUMBER |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Tooth Survival | Mineral Trioxide Aggregate | 158 | participants | ||
| Tooth Survival | Calcium Hydroxide | 130 | participants | ||
| Pulp Vitality | Mineral Trioxide Aggregate | 155 | participants | ||
| Pulp Vitality | Calcium Hydroxide | 130 | participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Mineral Trioxide Aggregate | 195 | |
| Overall Study | STARTED | Calcium Hydroxide | 181 | |
| Overall Study | COMPLETED | Mineral Trioxide Aggregate | 158 | |
| Overall Study | COMPLETED | Calcium Hydroxide | 130 | |
| Overall Study | NOT COMPLETED | Mineral Trioxide Aggregate | 37 | |
| Overall Study | NOT COMPLETED | Calcium Hydroxide | 51 |
Source ClinicalTrials.gov
Adverse events16
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Not feeling well | General disorders | Mineral Trioxide Aggregate | 1 | 195 | 1 |
| other | Not feeling well | General disorders | Calcium Hydroxide | 0 | 181 | 0 |
| other | H1N1 flu | Gastrointestinal disorders | Mineral Trioxide Aggregate | 1 | 195 | 1 |
| other | H1N1 flu | Gastrointestinal disorders | Calcium Hydroxide | 0 | 181 | 0 |
| other | Toothache on non-study tooth | Infections and infestations | Mineral Trioxide Aggregate | 3 | 195 | 3 |
| other | Toothache on non-study tooth | Infections and infestations | Calcium Hydroxide | 0 | 181 | 0 |
| other | Temperature sensitivity and dull ache in upper left quadrant | Infections and infestations | Mineral Trioxide Aggregate | 0 | 195 | 0 |
| other | Temperature sensitivity and dull ache in upper left quadrant | Infections and infestations | Calcium Hydroxide | 1 | 181 | 1 |
| other | Diabetes | Metabolism and nutrition disorders | Mineral Trioxide Aggregate | 0 | 195 | 0 |
| other | Diabetes | Metabolism and nutrition disorders | Calcium Hydroxide | 1 | 181 | 1 |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Mineral Trioxide Aggregate | ||
| Total, all-cause mortality | Calcium Hydroxide | ||
| Total, other adverse events | Mineral Trioxide Aggregate | 5 | 195 |
| Total, other adverse events | Calcium Hydroxide | 2 | 181 |
| Total, serious adverse events | Mineral Trioxide Aggregate | 2 | 195 |
| Total, serious adverse events | Calcium Hydroxide | 1 | 181 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| U01DE016750 | Network Chair for the Pacific Northwest DPBRN | DEROUEN, TIMOTHY A | UNIVERSITY OF WASHINGTON | NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH | 2005 to 2011 |
Source NIH RePORTER
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Mineral Trioxide Aggregate vs Calcium Hydroxide: Tooth Survival | Trial comparisons |
| Mineral Trioxide Aggregate vs Calcium Hydroxide: Pulp Vitality | Trial comparisons |
| Mineral Trioxide Aggregate vs Calcium Hydroxide: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00812877
GET https://conductscience.org/api/trials/v1/NCT00812877/registered