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Trial · NCT00823199

An Open Trial of Allopurinol in Patients With Poorly Responsive Schizophrenia

NCT00823199, Not applicable, Completed, Bronx Psychiatric Center; results first posted 2013-05-03

3 sourcestrials-2026-11-12-0.4.0

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ConductScience Library. An Open Trial of Allopurinol in Patients With Poorly Responsive Schizophrenia. Trials, record NCT00823199. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00823199

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
An Open Trial of Allopurinol in Patients With Poorly Responsive Schizophrenia
NCT number
NCT00823199
Status
Completed
Phases
Not applicable
Enrollment
10 participants, actual
Lead sponsor
Bronx Psychiatric Center
Conditions
Schizophrenia
Interventions
Allopurinal
First posted
2009-01-15
Last updated
2018-08-21
Results first posted
2013-05-03

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in Positive and Negative Syndrome Scale (PANSS) Measures Symptoms of Schizophreniabaseline and 4 weeksSymptom scale Score 30 (best, no symptoms of schizophrenia) to 210 (worst)
SecondarySimpson Angus Scale for Parkinsonismbaseline and 4 weeksMeasures drug induced parkinsonism, score 0 (best, no Parkinsonism) to 36 (worst)

Outcomes3

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYChange in Positive and Negative Syndrome Scale (PANSS) Measures Symptoms of Schizophreniabaseline and 4 weeksTwo subjects withdrew before the first week's evaluationscores on a scaleMEAN
SECONDARYSimpson Angus Scale for Parkinsonismbaseline and 4 weeksscore on scaleMEAN
POST_HOCUric Acid LevelBaseline and 4 weeks2 subjects had missing datamg/dLMEAN

Results by group6

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change in Positive and Negative Syndrome Scale (PANSS) Measures Symptoms of SchizophreniaAllopurinal TreatmentBaseline95Standard Deviation 22scores on a scale
Change in Positive and Negative Syndrome Scale (PANSS) Measures Symptoms of SchizophreniaAllopurinal TreatmentEnd75Standard Deviation 17scores on a scale
Simpson Angus Scale for ParkinsonismAllopurinal TreatmentBaseline0.37Standard Deviation 0.74score on scale
Simpson Angus Scale for ParkinsonismAllopurinal TreatmentEnd1.75Standard Deviation 3.1score on scale
Uric Acid LevelAllopurinal TreatmentBaseline5.9Standard Deviation 1.7mg/dL
Uric Acid LevelAllopurinal TreatmentEnd3.8Standard Deviation 0.7mg/dL

Participant flow3

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDAllopurinal Treatment10
Overall StudyCOMPLETEDAllopurinal Treatment8
Overall StudyNOT COMPLETEDAllopurinal Treatment2

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals3

The totals the trial posted for each group.

TotalGroupAffectedAt risk
Total, all-cause mortalityGroup 1
Total, other adverse eventsGroup 1010
Total, serious adverse eventsGroup 1010

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00823199

GET https://conductscience.org/api/trials/v1/NCT00823199/registered