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Trial · NCT00838383

Results by group207

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 0.5 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (1 mg/kg)-7.75Standard Deviation 55.277percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 0.5 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (2 mg/kg)-10.94Standard Deviation 37.967percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 0.5 Hour Post-separation From Cardiopulmonary Bypass (CPB)Placebo62.22Standard Deviation 260.172percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 6 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (1 mg/kg)39.36Standard Deviation 61.615percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 6 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (2 mg/kg)-12.01Standard Deviation 39.561percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 6 Hour Post-separation From Cardiopulmonary Bypass (CPB)Placebo173.68Standard Deviation 511.269percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 12 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (1 mg/kg)31.42Standard Deviation 67.887percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 12 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (2 mg/kg)-12.32Standard Deviation 37.517percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 12 Hour Post-separation From Cardiopulmonary Bypass (CPB)Placebo98.03Standard Deviation 283.333percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 24 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (1 mg/kg)18.06Standard Deviation 63.362percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 24 Hour Post-separation From Cardiopulmonary Bypass (CPB)Sitaxsentan (2 mg/kg)-15.99Standard Deviation 41.604percent change
Percent Change From 0 Hour in Pulmonary Vascular Resistance (PVR) at 24 Hour Post-separation From Cardiopulmonary Bypass (CPB)Placebo195.64Standard Deviation 522.379percent change
Mortality: Number of Participants Died During Surgery and Initial HospitalizationSitaxsentan (1 mg/kg)During surgery0participants
Mortality: Number of Participants Died During Surgery and Initial HospitalizationSitaxsentan (2 mg/kg)During surgery0participants
Mortality: Number of Participants Died During Surgery and Initial HospitalizationPlaceboDuring surgery0participants
Mortality: Number of Participants Died During Surgery and Initial HospitalizationSitaxsentan (1 mg/kg)During initial hospitalization2participants
Mortality: Number of Participants Died During Surgery and Initial HospitalizationSitaxsentan (2 mg/kg)During initial hospitalization1participants
Mortality: Number of Participants Died During Surgery and Initial HospitalizationPlaceboDuring initial hospitalization0participants
Number of Participants With Myocardial Infarction, Cerebrovascular Event, Hemodynamic Collapse and Re-operationSitaxsentan (1 mg/kg)Myocardial Infarction1participants
Number of Participants With Myocardial Infarction, Cerebrovascular Event, Hemodynamic Collapse and Re-operationSitaxsentan (2 mg/kg)Myocardial Infarction0participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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