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Trial · NCT00866281

Results by group90

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Maximum Tolerated Dose (MTD) of Midostaurin- Posterior Probability of DLTCohort 1: Midostaurin (30 Milligrams/Meters^2)Younger stratum (≥ 3months -≤ 2 years): (n=2, 5)0.0397.5% Confidence Interval 0 to 0.16probability estimates
Maximum Tolerated Dose (MTD) of Midostaurin- Posterior Probability of DLTCohort 2: Midostaurin (60 mg/m^2)Younger stratum (≥ 3months -≤ 2 years): (n=2, 5)0.1097.5% Confidence Interval 0.01 to 0.33probability estimates
Maximum Tolerated Dose (MTD) of Midostaurin- Posterior Probability of DLTCohort 1: Midostaurin (30 Milligrams/Meters^2)Older stratum (>2 years- <18years): (n=4,6)0.0397.5% Confidence Interval 0 to 0.13probability estimates
Maximum Tolerated Dose (MTD) of Midostaurin- Posterior Probability of DLTCohort 2: Midostaurin (60 mg/m^2)Older stratum (>2 years- <18years): (n=4,6)0.0897.5% Confidence Interval 0.01 to 0.26probability estimates
Percentage of Participants With Best Overall Response by IndicationAML SubjectsLeukemia free state0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsLeukemia free state0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsMorphological complete remission0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsMorphological complete remission0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsIncomplete morphological complete remission11.1Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsIncomplete morphological complete remission0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsPartial remission0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsPartial remission0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsBone marrow blast response22.2Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsBone marrow blast response0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsBone marrow minor blast response0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsBone marrow minor blast response0Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsPeripheral blood blast response11.1Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsPeripheral blood blast response23.1Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationAML SubjectsMinor peripheral blood blast response11.1Percentage of Participants
Percentage of Participants With Best Overall Response by IndicationMLLr-ALL SubjectsMinor peripheral blood blast response0Percentage of Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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