Trial · NCT00887757
Safety Study of ABT-263 in Combination With Gemzar (Gemcitabine) in Subjects With Solid Tumors
NCT00887757, Phase 1, Completed, AbbVie
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Safety Study of ABT-263 in Combination With Gemzar (Gemcitabine) in Subjects With Solid Tumors. Trials, record NCT00887757. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00887757
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety Study of ABT-263 in Combination With Gemzar (Gemcitabine) in Subjects With Solid Tumors
- NCT number
- NCT00887757
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 46 participants, actual
- Lead sponsor
- AbbVie
- Conditions
- Solid Tumors
- Interventions
- ABT-263, gemcitabine
- First posted
- 2009-04-24
- Last updated
- 2017-11-21
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Assess the safety profile of ABT-263 in combination with gemcitabine. | Weekly | |
| Primary | Study the pharmacokinetic interaction between ABT-263 and gemcitabine. | Weekly | |
| Primary | Determine the maximum tolerated dose (MTD) of ABT-263 in combination with gemcitabine. | Weekly | |
| Secondary | Evaluate safety at the defined recommended Phase 2 dose (RPTD) and schedule in combination with a standard and weekly regimen of gemcitabine. | Bi-monthly | |
| Secondary | Evaluate preliminary data regarding progression free survival (PFS) | Bi-monthly | |
| Secondary | Evaluate preliminary data regarding objective response rate (ORR) | Bi-monthly | |
| Secondary | Evaluate preliminary data regarding time to tumor progression (TTP) | Bi-monthly | |
| Secondary | Evaluate preliminary data regarding overall survival (OS) | Bi-monthly | |
| Secondary | Evaluate preliminary data regarding duration of overall response | Bi-monthly | |
| Secondary | Evaluate preliminary data with Eastern Cooperative Oncology Group (ECOG) performance status | Bi-monthly |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 24916770 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00887757
GET https://conductscience.org/api/trials/v1/NCT00887757/registered