Trial · NCT00893841
Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride
NCT00893841, Phase 2, Completed, Dr. D McIntosh & Dr. K Kjernisted Clinical Research Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride. Trials, record NCT00893841. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00893841
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride
- NCT number
- NCT00893841
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 96 participants, actual
- Lead sponsor
- Dr. D McIntosh & Dr. K Kjernisted Clinical Research Inc.
- Conditions
- Bipolar Depression
- Interventions
- quetiapine (Seroquel) XR, quetiapine (Seroquel) XR, placebo, pramipexole dihydrochloride
- First posted
- 2009-05-06
- Last updated
- 2013-02-04
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Montgomery-Asberg Depression Rating Scale (MADRS) total score | Week 0 to Week 16 | |
| Secondary | The mean change in MADRS total score | Week 0 to Week 8 | |
| Secondary | Proportion of subjects achieving remission (MADRS score of less than or equal to 10) | Week 16 | |
| Secondary | Proportion of subjects achieving response (reduction of at least 50% in MADRS total score) | Week 0 to Week 16 | |
| Secondary | Mean change in HAM-D 21 total score | Week 0 to Week 16 | |
| Secondary | Proportion of subjects achieving remission (HAM-D 21 total score of less than or equal to 7) | Week 16 | |
| Secondary | Proportion of subjects achieving treatment response (reduction of at least 50% in HAM-D 21 total score) | Week 0 to Week 16 | |
| Secondary | Mean change in Vancouver Semi-Structured Interview for Depression (V-SID) total score | Week 0 to Week 16 | |
| Secondary | Proportion of subjects withdrawing from study due to inadequate control of depressive symptoms | Week 0 - 16 | |
| Secondary | Change in neurocognitive function, assessed by CNS Vital Signs | Week 0 to Week 16 |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00893841
GET https://conductscience.org/api/trials/v1/NCT00893841/registered