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Trial · NCT00905424

Results by group92

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Augmentation Baseline for Non-Remitters in Montgomery-Ǻsberg Depression Rating Scale (MADRS) Total Score at Week 6 - Last Observation Carried Forward (LOCF)Antidepressant + SPD489 (Non-remitters)-7.1Standard Error 0.93Units on a scale
Change From Augmentation Baseline for Non-Remitters in Montgomery-Ǻsberg Depression Rating Scale (MADRS) Total Score at Week 6 - Last Observation Carried Forward (LOCF)Antidepressant + Placebo (Non-remitters)-4.9Standard Error 0.94Units on a scale
Change From Augmentation Baseline for Non-Remitters in the Hamilton Depression Scale (HAM-D) Total Score at Week 6 - LOCFAntidepressant + SPD489 (Non-remitters)-4.9Standard Error 0.64Units on a scale
Change From Augmentation Baseline for Non-Remitters in the Hamilton Depression Scale (HAM-D) Total Score at Week 6 - LOCFAntidepressant + Placebo (Non-remitters)-4.0Standard Error 0.65Units on a scale
Change From Augmentation Baseline for Non-Remitters in the Sheehan Disability Scale (SDS) Total Score at Week 6Antidepressant + SPD489 (Non-remitters)-3.7Standard Error 0.73Units on a scale
Change From Augmentation Baseline for Non-Remitters in the Sheehan Disability Scale (SDS) Total Score at Week 6Antidepressant + Placebo (Non-remitters)-1.7Standard Error 0.74Units on a scale
Percentage of Non-Remitters With Improvement on Clinical Global Impression-Improvement (CGI-I) at Week 6 - LOCFAntidepressant + SPD489 (Non-remitters)60.0Percent of Participants
Percentage of Non-Remitters With Improvement on Clinical Global Impression-Improvement (CGI-I) at Week 6 - LOCFAntidepressant + Placebo (Non-remitters)45.3Percent of Participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + SPD489 (Non-remitters)Normal, not at all ill1.5Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + Placebo (Non-remitters)Normal, not at all ill1.6Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + SPD489 (Non-remitters)Borderline mentally ill20.0Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + Placebo (Non-remitters)Borderline mentally ill12.5Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + SPD489 (Non-remitters)Mildly ill40.0Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + Placebo (Non-remitters)Mildly ill34.4Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + SPD489 (Non-remitters)Moderately ill32.3Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + Placebo (Non-remitters)Moderately ill48.4Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + SPD489 (Non-remitters)Markedly ill6.2Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + Placebo (Non-remitters)Markedly ill3.1Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + SPD489 (Non-remitters)Severely ill0Percent of participants
Assessment in Non-Remitters of Clinical Global Impression-Severity of Illness (CGI-S) at Augmentation BaselineAntidepressant + Placebo (Non-remitters)Severely ill0Percent of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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