Trial · NCT00924404
Xylitol Versus Saline in Chronic Sinusitis
NCT00924404, Not applicable, Completed, University of Iowa; results first posted 2017-08-09
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Xylitol Versus Saline in Chronic Sinusitis. Trials, record NCT00924404. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00924404
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Xylitol Versus Saline in Chronic Sinusitis
- NCT number
- NCT00924404
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 53 participants, actual
- Lead sponsor
- University of Iowa
- Conditions
- Chronic Sinusitis
- Interventions
- Xylitol, Saline
- First posted
- 2009-06-19
- Last updated
- 2018-08-31
- Results first posted
- 2017-08-09
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | SNOT-20 Scores at 12 Weeks | 12 weeks | Sinonasal outcome test is a 20 item quality of life questionnaire: Min-Max score range 0-100 The SNOT score for each patient was defined as the mean value of the response to the 20 items. The questionnaire is divided into 4 subsets, symptoms related to nose, symptoms of ear and face, sleep quality and psychological issues. Symptoms arereported on 100 mm visual analog scales (VASs) where 0 mm represents no symptoms and 100 mm represent "as troublesome as possible". The symptom severity is considered mild between 0 and 30, moderate from 30 to 70 and severe from 70- 100. |
| Secondary | Mean Number of Antibiotic Courses During the Study Period | 12 weeks | Mean Number of antibiotic courses for infection during the study period |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | SNOT-20 Scores at 12 Weeks | 12 weeks | We initially enrolled 53 subjects but we had 10 subjects drop out of the study. | units on a scale | MEAN |
| SECONDARY | Mean Number of Antibiotic Courses During the Study Period | 12 weeks | mean number of antibiotic courses during | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| SNOT-20 Scores at 12 Weeks | Xylitol | 7 | Standard Deviation 15 | units on a scale | |
| SNOT-20 Scores at 12 Weeks | Saline | 11 | Standard Deviation 16 | units on a scale | |
| Mean Number of Antibiotic Courses During the Study Period | Xylitol | 1.90 | Standard Deviation 0.30 | mean number of antibiotic courses during | |
| Mean Number of Antibiotic Courses During the Study Period | Saline | 1.77 | Standard Deviation 0.43 | mean number of antibiotic courses during |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Xylitol | 27 | |
| Overall Study | STARTED | Saline | 26 | |
| Overall Study | COMPLETED | Xylitol | 21 | |
| Overall Study | COMPLETED | Saline | 22 | |
| Overall Study | NOT COMPLETED | Xylitol | 6 | |
| Overall Study | NOT COMPLETED | Saline | 4 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Xylitol | 0 | 21 |
| Total, all-cause mortality | Saline | 0 | 22 |
| Total, other adverse events | Xylitol | 0 | 21 |
| Total, other adverse events | Saline | 0 | 22 |
| Total, serious adverse events | Xylitol | 0 | 21 |
| Total, serious adverse events | Saline | 0 | 22 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Xylitol vs Saline: deaths from any cause | Trial comparisons |
| Xylitol vs Saline: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00924404
GET https://conductscience.org/api/trials/v1/NCT00924404/registered