Trial · NCT00941668
Evaluate Inflammation Caused by Gingivitis in Adults
NCT00941668, Phase 4, Completed, Colgate Palmolive; results first posted 2009-07-17
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Evaluate Inflammation Caused by Gingivitis in Adults. Trials, record NCT00941668. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00941668
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Evaluate Inflammation Caused by Gingivitis in Adults
- NCT number
- NCT00941668
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 49 participants, actual
- Lead sponsor
- Colgate Palmolive
- Conditions
- Gingivitis
- Interventions
- Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
- First posted
- 2009-07-17
- Last updated
- 2015-08-27
- Results first posted
- 2009-07-17
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Level of Gingival Crevicular Fluid Interleukin - 1 (GCF IL-1) at 2 Hours | 4 weeks | Levels of Gingival crevicular fluid Interleukin - 1 (GCF IL-1)(weight in micrograms) |
| Primary | Level of Gingival Crevicular Fluid Interleukin - 6(GCF IL-6) at 2 Hours | 4 weeks | Levels of Gingival crevicular fluid Interleukin - 6 (GCF IL-6) (weight in micrograms) |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Level of Gingival Crevicular Fluid Interleukin - 1 (GCF IL-1) at 2 Hours | 4 weeks | Micrograms | MEAN | |
| PRIMARY | Level of Gingival Crevicular Fluid Interleukin - 6(GCF IL-6) at 2 Hours | 4 weeks | Micrograms | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Level of Gingival Crevicular Fluid Interleukin - 1 (GCF IL-1) at 2 Hours | Total Toothpaste (Active) | 492.2 | Standard Deviation 545.5 | Micrograms | |
| Level of Gingival Crevicular Fluid Interleukin - 1 (GCF IL-1) at 2 Hours | Colgate Cavity Protection (Placebo) | 326.3 | Standard Deviation 307.7 | Micrograms | |
| Level of Gingival Crevicular Fluid Interleukin - 6(GCF IL-6) at 2 Hours | Total Toothpaste (Active) | 12.8 | Standard Deviation 23.3 | Micrograms | |
| Level of Gingival Crevicular Fluid Interleukin - 6(GCF IL-6) at 2 Hours | Colgate Cavity Protection (Placebo) | 21.3 | Standard Deviation 46.4 | Micrograms |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Total Toothpaste (Active) | 24 | |
| Overall Study | STARTED | Colgate Great Regular Flavor (Placebo) | 25 | |
| Overall Study | COMPLETED | Total Toothpaste (Active) | 0 | |
| Overall Study | COMPLETED | Colgate Great Regular Flavor (Placebo) | 0 | |
| Overall Study | NOT COMPLETED | Total Toothpaste (Active) | 24 | |
| Overall Study | NOT COMPLETED | Colgate Great Regular Flavor (Placebo) | 25 |
Source ClinicalTrials.gov
Adverse events8
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Tooth Sensitivity to Cold | General disorders | Total Toothpaste (Active) | 1 | 24 | 1 |
| other | Tooth Sensitivity to Cold | General disorders | Colgate Cavity Protection (Placebo) | 2 | 25 | 2 |
| other | Oral irritation | General disorders | Total Toothpaste (Active) | 1 | 24 | 1 |
| other | Oral irritation | General disorders | Colgate Cavity Protection (Placebo) | 1 | 25 | 1 |
| other | Cold and/or flu like symptoms | General disorders | Total Toothpaste (Active) | 1 | 24 | 1 |
| other | Cold and/or flu like symptoms | General disorders | Colgate Cavity Protection (Placebo) | 2 | 25 | 2 |
| other | pulled muscle | General disorders | Total Toothpaste (Active) | 1 | 24 | 1 |
| other | pulled muscle | General disorders | Colgate Cavity Protection (Placebo) | 1 | 25 | 1 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Total Toothpaste (Active) | ||
| Total, all-cause mortality | Colgate Cavity Protection (Placebo) | ||
| Total, other adverse events | Total Toothpaste (Active) | 1 | 24 |
| Total, other adverse events | Colgate Cavity Protection (Placebo) | 6 | 25 |
| Total, serious adverse events | Total Toothpaste (Active) | 0 | 24 |
| Total, serious adverse events | Colgate Cavity Protection (Placebo) | 0 | 25 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Total Toothpaste (Active) vs Colgate Cavity Protection (Placebo): serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00941668
GET https://conductscience.org/api/trials/v1/NCT00941668/registered