Trial · NCT00952523
Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
NCT00952523, Phase 4, Completed, Bausch Health Americas, Inc.; results first posted 2010-04-09
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face. Trials, record NCT00952523. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00952523
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
- NCT number
- NCT00952523
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 162 participants, actual
- Lead sponsor
- Bausch Health Americas, Inc.
- Conditions
- Acne Vulgaris
- Interventions
- Tretinoin Facial Gel, Adapalene/Benzoyl Peroxide Facial Gel
- First posted
- 2009-08-06
- Last updated
- 2012-02-15
- Results first posted
- 2010-04-09
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Facial Irritation and Cutaneous Effects | three weeks | Scores on a scale were recorded each weekday. The scale for Erythema and Dryness was from 0=none to 8=severe (highest possible score is calculated as 8x5daysx3weeks=120). The scale for Burning/Stinging and Itching was from 0=none to 3=severe (highest possible score was calculated as 3x5daysx3weeks=45). The scores that were accumulated through the study for each treatment were then compared. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Facial Irritation and Cutaneous Effects | three weeks | Scores on a Scale | MEAN |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Facial Irritation and Cutaneous Effects | Tretinoin Facial Gel | Erythema | 1.5 | Standard Deviation 3.8 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Adapalene-Benzoyl Peroxide Facial Gel | Erythema | 5.4 | Standard Deviation 11.8 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Tretinoin Facial Gel | Dryness | 3.1 | Standard Deviation 6.1 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Adapalene-Benzoyl Peroxide Facial Gel | Dryness | 7.8 | Standard Deviation 10.3 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Tretinoin Facial Gel | Burning/Stinging | 1.9 | Standard Deviation 4.0 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Adapalene-Benzoyl Peroxide Facial Gel | Burning/Stinging | 5.8 | Standard Deviation 6.5 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Tretinoin Facial Gel | Itching | 1.0 | Standard Deviation 2.3 | Scores on a Scale |
| Facial Irritation and Cutaneous Effects | Adapalene-Benzoyl Peroxide Facial Gel | Itching | 2.9 | Standard Deviation 4.4 | Scores on a Scale |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Tretinoin & Adapalene-Benzoyl Peroxide | 162 | |
| Overall Study | COMPLETED | Tretinoin & Adapalene-Benzoyl Peroxide | 155 | |
| Overall Study | NOT COMPLETED | Tretinoin & Adapalene-Benzoyl Peroxide | 7 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Tretinoin Facial Gel | ||
| Total, all-cause mortality | Adapalene-Benzoyl Peroxide Facial Gel | ||
| Total, other adverse events | Tretinoin Facial Gel | 0 | 162 |
| Total, other adverse events | Adapalene-Benzoyl Peroxide Facial Gel | 0 | 162 |
| Total, serious adverse events | Tretinoin Facial Gel | 0 | 162 |
| Total, serious adverse events | Adapalene-Benzoyl Peroxide Facial Gel | 0 | 162 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 20684151 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Tretinoin Facial Gel vs Adapalene-Benzoyl Peroxide Facial Gel: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00952523
GET https://conductscience.org/api/trials/v1/NCT00952523/registered