Trial · NCT00955929
Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy
NCT00955929, Not applicable, Terminated, Memorial Sloan Kettering Cancer Center; results first posted 2021-11-08
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy. Trials, record NCT00955929. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00955929
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy
- NCT number
- NCT00955929
- Status
- Terminated
- Phases
- Not applicable
- Enrollment
- 76 participants, actual
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Conditions
- Penile Cancer, Erectile Dysfunction, Radical Prostatectomy
- Interventions
- Placebo QHS and sildenafil and questionnaires, Sildenafil and questionnaire, Trimix combination (Papavarine 30mg/mL Phentholamine 1mg/mL Prostaglandin E1 10 mcg/mmL) and questionnaires
- First posted
- 2009-08-10
- Last updated
- 2021-11-10
- Results first posted
- 2021-11-08
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Difference in the Erectile Function (EF) Domain Score of the International Index of Erectile Function (IIEF) Between the 3 Groups at 24 Months. | 2 years | |
| Secondary | The Time to Return of Spontaneous Functional Erections. | 2 years | |
| Secondary | The Time for Patients to Respond to Oral Erectogenic Therapy. | 2 years | |
| Secondary | The Proportion of Patients Who Have Normalization of Their Erectile Function (Normalization of the EF Domain of the IIEF). | 2 years |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Difference in the Erectile Function (EF) Domain Score of the International Index of Erectile Function (IIEF) Between the 3 Groups at 24 Months. | 2 years | Data were not collected | ||
| SECONDARY | The Time to Return of Spontaneous Functional Erections. | 2 years | Data were not collected | ||
| SECONDARY | The Time for Patients to Respond to Oral Erectogenic Therapy. | 2 years | Data were not collected | ||
| SECONDARY | The Proportion of Patients Who Have Normalization of Their Erectile Function (Normalization of the EF Domain of the IIEF). | 2 years | Data were not collected |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | PRN Sildenafil | 13 | |
| Overall Study | STARTED | Nightly Sildenafil Arm | 30 | |
| Overall Study | STARTED | Combination Therapy Arm | 33 | |
| Overall Study | COMPLETED | PRN Sildenafil | 13 | |
| Overall Study | COMPLETED | Nightly Sildenafil Arm | 30 | |
| Overall Study | COMPLETED | Combination Therapy Arm | 33 | |
| Overall Study | NOT COMPLETED | PRN Sildenafil | 0 | |
| Overall Study | NOT COMPLETED | Nightly Sildenafil Arm | 0 | |
| Overall Study | NOT COMPLETED | Combination Therapy Arm | 0 |
Source ClinicalTrials.gov
Adverse events9
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Wound complication, non-infectious | Injury, poisoning and procedural complications | PRN Sildenafil | 0 | 13 | |
| serious | Wound complication, non-infectious | Injury, poisoning and procedural complications | Nightly Sildenafil Arm | 1 | 30 | |
| serious | Wound complication, non-infectious | Injury, poisoning and procedural complications | Combination Therapy Arm | 0 | 33 | |
| serious | Infection w/ Gr 3/4 neut, Pelvis NOS | Infections and infestations | PRN Sildenafil | 0 | 13 | |
| serious | Infection w/ Gr 3/4 neut, Pelvis NOS | Infections and infestations | Nightly Sildenafil Arm | 0 | 30 | |
| serious | Infection w/ Gr 3/4 neut, Pelvis NOS | Infections and infestations | Combination Therapy Arm | 1 | 33 | |
| serious | Pain - Extremity-limb | Musculoskeletal and connective tissue disorders | PRN Sildenafil | 0 | 13 | |
| serious | Pain - Extremity-limb | Musculoskeletal and connective tissue disorders | Nightly Sildenafil Arm | 0 | 30 | |
| serious | Pain - Extremity-limb | Musculoskeletal and connective tissue disorders | Combination Therapy Arm | 1 | 33 |
Source ClinicalTrials.gov
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | PRN Sildenafil | 0 | 13 |
| Total, all-cause mortality | Nightly Sildenafil Arm | 2 | 30 |
| Total, all-cause mortality | Combination Therapy Arm | 0 | 33 |
| Total, other adverse events | PRN Sildenafil | 0 | 13 |
| Total, other adverse events | Nightly Sildenafil Arm | 0 | 30 |
| Total, other adverse events | Combination Therapy Arm | 0 | 33 |
| Total, serious adverse events | PRN Sildenafil | 0 | 13 |
| Total, serious adverse events | Nightly Sildenafil Arm | 1 | 30 |
| Total, serious adverse events | Combination Therapy Arm | 2 | 33 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00955929
GET https://conductscience.org/api/trials/v1/NCT00955929/registered