Trial · NCT01002482

Computerized Glucose Control in Critically Ill Patients

NCT01002482, Phase 3, Completed, Centre Hospitalier of Chartres; results first posted 2013-12-03

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Computerized Glucose Control in Critically Ill Patients. Trials, record NCT01002482. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01002482

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Computerized Glucose Control in Critically Ill Patients
NCT number: NCT01002482
Status: Completed
Phases: Phase 3
Enrollment: 2,684 participants, actual
Lead sponsor: Centre Hospitalier of Chartres
Conditions: Hyperglycemia, Critical Illness
Interventions: CGAO-based Glucose Control, Standard-Care Glucose Control
First posted: 2009-10-27
Last updated: 2013-12-03
Results first posted: 2013-12-03

Source ClinicalTrials.gov

Registered outcomes10

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	All-cause 90-day Mortality	Day 90
Secondary	All-cause 28-day Mortality	Day 28
Secondary	All-cause Intensive Care Unit Mortality	Date of discharge from the ICU
Secondary	All-cause In-hospital Mortality	Day of discharge from the hospital
Secondary	Intensive Care Unit Free Days	28 days	Intensive care unit free days was 28-day-ICU-free-days i.e. was calculated by subtracting the actual ICU duration in days from 28 with patients who died at day 28 or before being assigned 0 free-days and those who had a stay in ICU of 28 days or more being also assigned 0 free-days
Secondary	Time Spent in Blood Glucose Target	Day of discharge from the ICU
Secondary	Severe Hypoglycemia	Date of discharge from the ICU	Number of patients with severe biological hypoglycemia (defined as blood glucose of 40 mg per deciliter or less)regardless of clinical signs
Secondary	Hospital Length of Stay	Date of discharge from the hospital
Secondary	Intensive Care Unit Length of Stay	Date of discharge from the ICU
Secondary	Incidence of Nosocomial Bacteriemia	Date of discharge from the ICU

Source ClinicalTrials.gov

Outcomes10

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Units	Measured as
PRIMARY	All-cause 90-day Mortality	Day 90	participants	NUMBER
SECONDARY	All-cause 28-day Mortality	Day 28	participants	NUMBER
SECONDARY	All-cause Intensive Care Unit Mortality	Date of discharge from the ICU	participants	NUMBER
SECONDARY	All-cause In-hospital Mortality	Day of discharge from the hospital	participants	NUMBER
SECONDARY	Intensive Care Unit Free Days	28 days	days	MEDIAN
SECONDARY	Time Spent in Blood Glucose Target	Day of discharge from the ICU
SECONDARY	Severe Hypoglycemia	Date of discharge from the ICU	participants	NUMBER
SECONDARY	Hospital Length of Stay	Date of discharge from the hospital	days	MEDIAN
SECONDARY	Intensive Care Unit Length of Stay	Date of discharge from the ICU	days	MEDIAN
SECONDARY	Incidence of Nosocomial Bacteriemia	Date of discharge from the ICU

Source ClinicalTrials.gov

Results by group16

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Spread	Units
All-cause 90-day Mortality	CGAO-based Glucose Control	431		participants
All-cause 90-day Mortality	Standard-Care Glucose Gontrol	447		participants
All-cause 28-day Mortality	CGAO-based Glucose Control	326		participants
All-cause 28-day Mortality	Standard-Care Glucose Gontrol	328		participants
All-cause Intensive Care Unit Mortality	CGAO-based Glucose Control	302		participants
All-cause Intensive Care Unit Mortality	Standard-Care Glucose Gontrol	310		participants
All-cause In-hospital Mortality	CGAO-based Glucose Control	376		participants
All-cause In-hospital Mortality	Standard-Care Glucose Gontrol	393		participants
Intensive Care Unit Free Days	CGAO-based Glucose Control	14	Inter-Quartile Range 0 to 22	days
Intensive Care Unit Free Days	Standard-Care Glucose Gontrol	13	Inter-Quartile Range 0 to 23	days

1 to 10 of 16Source ClinicalTrials.gov

See all 16 results by group

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	CGAO-based Glucose Control	1,351
Overall Study	STARTED	Standard-Care Glucose Gontrol	1,333
Overall Study	COMPLETED	CGAO-based Glucose Control	1,336
Overall Study	COMPLETED	Standard-Care Glucose Gontrol	1,312
Overall Study	NOT COMPLETED	CGAO-based Glucose Control	15
Overall Study	NOT COMPLETED	Standard-Care Glucose Gontrol	21

Source ClinicalTrials.gov

Adverse events2

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
serious	BG of 40 mg per deciliter or less accompanied with observed or suspected neurological symptoms	Metabolism and nutrition disorders	CGAO-based Glucose Control	20	1,336	23
serious	BG of 40 mg per deciliter or less accompanied with observed or suspected neurological symptoms	Metabolism and nutrition disorders	Standard-Care Glucose Gontrol	6	1,312	9

Source ClinicalTrials.gov

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	CGAO-based Glucose Control
Total, all-cause mortality	Standard-Care Glucose Gontrol
Total, other adverse events	CGAO-based Glucose Control	0	1,336
Total, other adverse events	Standard-Care Glucose Gontrol	0	1,312
Total, serious adverse events	CGAO-based Glucose Control	20	1,336
Total, serious adverse events	Standard-Care Glucose Gontrol	6	1,312

Source ClinicalTrials.gov

Papers4

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
18183643	BACKGROUND	PubMed
19500942	BACKGROUND	PubMed
24420499	DERIVED	PubMed
25888011	DERIVED	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons6

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
CGAO-based Glucose Control vs Standard-Care Glucose Gontrol: All-cause In-hospital Mortality	Trial comparisons
CGAO-based Glucose Control vs Standard-Care Glucose Gontrol: All-cause 28-day Mortality	Trial comparisons
CGAO-based Glucose Control vs Standard-Care Glucose Gontrol: Severe Hypoglycemia	Trial comparisons
CGAO-based Glucose Control vs Standard-Care Glucose Gontrol: All-cause 90-day Mortality	Trial comparisons
CGAO-based Glucose Control vs Standard-Care Glucose Gontrol: All-cause Intensive Care Unit Mortality	Trial comparisons
CGAO-based Glucose Control vs Standard-Care Glucose Gontrol: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT01002482

GET https://conductscience.org/api/trials/v1/NCT01002482/registered

API reference For AI assistants