Trial · NCT01023659
Distribution of Bupropion and Varenicline to Increase Smoking Cessation Attempts
NCT01023659, Phase 4, Completed, Centre for Addiction and Mental Health; results first posted 2013-03-15
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Distribution of Bupropion and Varenicline to Increase Smoking Cessation Attempts. Trials, record NCT01023659. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01023659
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Distribution of Bupropion and Varenicline to Increase Smoking Cessation Attempts
- NCT number
- NCT01023659
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 893 participants, actual
- Lead sponsor
- Centre for Addiction and Mental Health
- Conditions
- Tobacco Use Disorder, Smoking, Smoking Cessation
- Interventions
- bupropion, varenicline, motivational emails
- First posted
- 2009-12-02
- Last updated
- 2018-01-24
- Results first posted
- 2013-03-15
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 7-day Point Prevalence of Abstinence | 6-month | 7-day point prevalence of abstinence was assessed by the question "Have you had a cigarette, even a puff, in the past 7 days?" |
| Primary | Proportion of Eligible Participants Who Were Able to Attend an Appointment With a Physician | End of Treatment | Proportion of eligible participants who were able to attend an appointment with a physician to have the prescription signed |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | 7-day Point Prevalence of Abstinence | 6-month | Number of eligible participants who either received bupropion + motivational emails, varenicline + motivational emails or motivational emails alone (because they either did not attend a physician visit or their physician decided not to prescribe them bupropion or varenicline) | Participants | COUNT_OF_PARTICIPANTS |
| PRIMARY | Proportion of Eligible Participants Who Were Able to Attend an Appointment With a Physician | End of Treatment | total number of eligible participants in study | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| 7-day Point Prevalence of Abstinence | Bupropion + Motivational Emails | 45 | Participants | ||
| 7-day Point Prevalence of Abstinence | Motivational Emails | 22 | Participants | ||
| 7-day Point Prevalence of Abstinence | Varenicline + Motivational Emails | 50 | Participants | ||
| Proportion of Eligible Participants Who Were Able to Attend an Appointment With a Physician | All Eligible Participants | 588 | Participants |
Source ClinicalTrials.gov
Participant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Bupropion + Motivational Emails | 258 | |
| Overall Study | STARTED | Motivational Emails | 365 | |
| Overall Study | STARTED | Varenicline + Motivational Emails | 264 | |
| Overall Study | COMPLETED | Bupropion + Motivational Emails | 185 | |
| Overall Study | COMPLETED | Motivational Emails | 137 | |
| Overall Study | COMPLETED | Varenicline + Motivational Emails | 165 | |
| Overall Study | NOT COMPLETED | Bupropion + Motivational Emails | 73 | |
| Overall Study | NOT COMPLETED | Motivational Emails | 228 | |
| Overall Study | NOT COMPLETED | Varenicline + Motivational Emails | 99 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Bupropion + Motivational Emails | ||
| Total, all-cause mortality | Motivational Emails | ||
| Total, all-cause mortality | Varenicline + Motivational Emails | ||
| Total, other adverse events | Bupropion + Motivational Emails | 0 | 0 |
| Total, other adverse events | Motivational Emails | 0 | 0 |
| Total, other adverse events | Varenicline + Motivational Emails | 0 | 0 |
| Total, serious adverse events | Bupropion + Motivational Emails | 0 | 0 |
| Total, serious adverse events | Motivational Emails | 0 | 0 |
| Total, serious adverse events | Varenicline + Motivational Emails | 0 | 0 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 26429100 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01023659
GET https://conductscience.org/api/trials/v1/NCT01023659/registered