Trial · NCT01045122
Sedation in Patients at Risk for Upper Airway Collapse
NCT01045122, Not applicable, Completed, University of Rochester; results first posted 2015-04-27
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Sedation in Patients at Risk for Upper Airway Collapse. Trials, record NCT01045122. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01045122
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Sedation in Patients at Risk for Upper Airway Collapse
- NCT number
- NCT01045122
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 15 participants, actual
- Lead sponsor
- University of Rochester
- Conditions
- Obstructive Sleep Apnea
- Interventions
- Propofol, Dexmedetomidine
- First posted
- 2010-01-08
- Last updated
- 2015-04-27
- Results first posted
- 2015-04-27
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Respiratory Disturbance Index | during infusion of study drugs | respiratory events (apneas, hypopneas) per hour |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Respiratory Disturbance Index | during infusion of study drugs | Per protocol | events per hour | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Respiratory Disturbance Index | Propofol | 57.52 | Standard Deviation 165.6 | events per hour | |
| Respiratory Disturbance Index | Dexmedetomidine | 21.32 | Standard Deviation 39.2 | events per hour |
Source ClinicalTrials.gov
Participant flow12
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Dexmedetomidine Then Propofol | STARTED | Propofol First | 5 | |
| Dexmedetomidine Then Propofol | STARTED | Dexmedetomidine First | 6 | |
| Dexmedetomidine Then Propofol | COMPLETED | Propofol First | 5 | |
| Dexmedetomidine Then Propofol | COMPLETED | Dexmedetomidine First | 6 | |
| Dexmedetomidine Then Propofol | NOT COMPLETED | Propofol First | 0 | |
| Dexmedetomidine Then Propofol | NOT COMPLETED | Dexmedetomidine First | 0 | |
| Propofol Then Dexmedetomidine | STARTED | Propofol First | 5 | |
| Propofol Then Dexmedetomidine | STARTED | Dexmedetomidine First | 6 | |
| Propofol Then Dexmedetomidine | COMPLETED | Propofol First | 5 | |
| Propofol Then Dexmedetomidine | COMPLETED | Dexmedetomidine First | 6 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 participant flowAdverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Propofol | ||
| Total, all-cause mortality | Dexmedetomidine | ||
| Total, other adverse events | Propofol | 0 | 11 |
| Total, other adverse events | Dexmedetomidine | 0 | 11 |
| Total, serious adverse events | Propofol | 0 | 11 |
| Total, serious adverse events | Dexmedetomidine | 0 | 11 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| M01RR000044 | General Clinical Research Center | GUZICK, DAVID S | UNIVERSITY OF ROCHESTER | NATIONAL CENTER FOR RESEARCH RESOURCES | 1985 to 2006 |
Source NIH RePORTER
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Propofol vs Dexmedetomidine: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01045122
GET https://conductscience.org/api/trials/v1/NCT01045122/registered