Trial · NCT01065714
A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis
NCT01065714, Phase 4, Completed, Derm Research, PLLC; results first posted 2013-04-25
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis. Trials, record NCT01065714. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01065714
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis
- NCT number
- NCT01065714
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 20 participants, actual
- Lead sponsor
- Derm Research, PLLC
- Conditions
- Atopic Dermatitis
- Interventions
- Hydrogel vehicle, Eucerin Lotion
- First posted
- 2010-02-09
- Last updated
- 2013-04-25
- Results first posted
- 2013-04-25
- Limitations and caveats
- Small number of participants, pilot study, short term
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percent Change of Trans Epidermal Water Loss (TEWL) With Use of Eucerin Lotion | Day 1 to Day 14 | The average of three sequential Tewameter 300 meter readings taken at a minimum of one minute intervals on targeted area of body half treated with Eucerin lotion |
| Primary | Percent Change of Trans Epidural Water Loss (TEWL) With the Use of Hydrogel Vehicle | Day 1 to Day 14 | The average of three sequential Tewameter 300 meter readings taken at a minimum of one minute intervals on target areas of body half treated with Hydrogel vehicle |
| Secondary | Percentage of Participants With an Increase in Skin Hydration Using Eucerin Lotion on Targeted Area on One Half of Body | Baseline to 14 days | Five timed readings ( 0, 15, 30, 45 and 60 minutes) were taken using the Corneometer 825 meter on subjects using Eucerin lotion on targeted area on one half of body |
| Secondary | Percentage of Participants With an Increase in Skin Hydration Using Hydrogel Vehicle on Targeted Area of One Half of Body. | Baseline to 14 days | Five timed readings at (0, 15, 30, 45 and 60 minutes) were taken, using the Corneometer 825 meter, on participants using Hydrogel vehicle |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Percent Change of Trans Epidermal Water Loss (TEWL) With Use of Eucerin Lotion | Day 1 to Day 14 | per protocol | percent change | MEDIAN |
| PRIMARY | Percent Change of Trans Epidural Water Loss (TEWL) With the Use of Hydrogel Vehicle | Day 1 to Day 14 | Per protocol | percent change | MEDIAN |
| SECONDARY | Percentage of Participants With an Increase in Skin Hydration Using Eucerin Lotion on Targeted Area on One Half of Body | Baseline to 14 days | per protocol | Percentage of participants | MEAN |
| SECONDARY | Percentage of Participants With an Increase in Skin Hydration Using Hydrogel Vehicle on Targeted Area of One Half of Body. | Baseline to 14 days | per protocol | percentage of participants | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Percent Change of Trans Epidermal Water Loss (TEWL) With Use of Eucerin Lotion | Skin Barrier Function With Eucerin Lotion | 21.4 | Full Range 54.8 | percent change | |
| Percent Change of Trans Epidural Water Loss (TEWL) With the Use of Hydrogel Vehicle | Skin Barrier Function With Hydrogel Vehicle | 4.2 | Full Range 31.2 | percent change | |
| Percentage of Participants With an Increase in Skin Hydration Using Eucerin Lotion on Targeted Area on One Half of Body | Skin Hydration With Eucerin | 33.5 | Standard Deviation 72.2 | Percentage of participants | |
| Percentage of Participants With an Increase in Skin Hydration Using Hydrogel Vehicle on Targeted Area of One Half of Body. | Skin Hydration With Hydrogel | 32.3 | Standard Deviation 51.5 | percentage of participants |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Hydrogel Vehicle/Eucerin Lotion | 20 | |
| Overall Study | COMPLETED | Hydrogel Vehicle/Eucerin Lotion | 20 | |
| Overall Study | NOT COMPLETED | Hydrogel Vehicle/Eucerin Lotion | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Hydrogel Vehicle/Eucerin Lotion | ||
| Total, other adverse events | Hydrogel Vehicle/Eucerin Lotion | 0 | 20 |
| Total, serious adverse events | Hydrogel Vehicle/Eucerin Lotion | 0 | 20 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01065714
GET https://conductscience.org/api/trials/v1/NCT01065714/registered