Trial · NCT01096082
Safety and Efficacy of Lithium Carbonate in Patients With Spinocerebellar Ataxia Type 3
NCT01096082, Phase 2, Phase 3, Completed, Hospital de Clinicas de Porto Alegre
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety and Efficacy of Lithium Carbonate in Patients With Spinocerebellar Ataxia Type 3. Trials, record NCT01096082. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01096082
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety and Efficacy of Lithium Carbonate in Patients With Spinocerebellar Ataxia Type 3
- NCT number
- NCT01096082
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 62 participants, actual
- Lead sponsor
- Hospital de Clinicas de Porto Alegre
- Conditions
- Spinocerebellar Ataxia Type 3, Machado Joseph Disease
- Interventions
- Lithium Carbonate, Placebo
- First posted
- 2010-03-30
- Last updated
- 2013-01-30
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Phase 2 - Safety and tolerability of Lithium Carbonate treatment in patients with SCA3 | 6 months | According to the Common toxicity criteria manual, version 2.0 |
| Primary | Phase 3 - Efficacy of Lithium Carbonate treatment in patients with SCA3 | 12 months | Application of the Neurological Examination Score for SCA 3 (NESSCA) |
| Secondary | Efficacy of Lithium Carbonate in patients with SCA3 on neurological function, ataxic, depressive and quality of life scores | 6 and 12 months | Scale for the Assessment and Rating of Ataxia (SARA), 9-Hole Peg Board test, 8m walking time, PATA repetition rate, Click Test, SCA Functional Index (SCAFI), Composite Cerebellar Functional Score (CCFS), Beck Depression Inventory, Barthel Index and WHOQol |
| Secondary | Effect of Lithium Carbonate treatment in peripheral levels and expression of treatment biomarkers | 3 and 6 months | BDNF, NSE, HDAC, GSK-3Beta |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01096082
GET https://conductscience.org/api/trials/v1/NCT01096082/registered