Trial · NCT01100892
Cystic Fibrosis - Insulin Deficiency, Early Action
NCT01100892, Phase 3, Completed, Sydney Children's Hospitals Network
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cystic Fibrosis - Insulin Deficiency, Early Action. Trials, record NCT01100892. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01100892
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cystic Fibrosis - Insulin Deficiency, Early Action
- NCT number
- NCT01100892
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Sydney Children's Hospitals Network
- Conditions
- Cystic Fibrosis, Diabetes
- Interventions
- Once-daily insulin detemir
- First posted
- 2010-04-09
- Last updated
- 2023-05-31
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Weight SDS (Standard Deviation Score) | 12 months | |
| Primary | Change in lung function (FEV1, FVC) | 12 months | |
| Secondary | Reduced rate of decline in glycaemic category, comparing OGTT at baseline and 12 months. | 12 months | OGTT = Oral Glucose Tolerance Test |
| Secondary | Reduced frequency of hospitalisation for acute respiratory illness | 12 months | |
| Secondary | Change in glycaemic status assessed by HbA1c and CGM | 12 months | CGM = Continuous Glucose Monitoring |
| Secondary | Body composition by DEXA. Patients at CHW will also have pQCT. | 12 months | DEXA = Dual Energy X-ray Absorptiometry pQCT = peripheral Quantitative Computed Tomography |
| Secondary | Change in Grip-strength | 12 months | |
| Secondary | Improved quality of life, measured by a validated CF QOL questionnaire | 12 months | |
| Secondary | Bacterial colonisation of sputum | 12 months | |
| Secondary | Change in effort-dependent lung function: MIP, MEP, SnIP | 12 months | MIP = Mouth Inspiratory Pressure MEP = Mouth Expiratory Pressure SnIP = Sniff Nasal Inspiratory Pressure |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01100892
GET https://conductscience.org/api/trials/v1/NCT01100892/registered