Trial · NCT01110252
Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease
NCT01110252, Not applicable, Completed, UPECLIN HC FM Botucatu Unesp; results first posted 2012-03-26
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease. Trials, record NCT01110252. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01110252
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety Study of Cell Therapy to Treat Chronic Obstructive Pulmonary Disease
- NCT number
- NCT01110252
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 4 participants, actual
- Lead sponsor
- UPECLIN HC FM Botucatu Unesp
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema
- Interventions
- Stem cells stimulation, stem cells collection, stem cells infusion
- First posted
- 2010-04-26
- Last updated
- 2012-03-26
- Results first posted
- 2012-03-26
- Limitations and caveats
- small number of subjects analyzed
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Forced Vital Capacity (FVC) | baseline and 30 days after procedure | A pulmonary function test that measures the volume and speed of the inhalated air. |
| Primary | Forced Expiratory Volume (FEV1) | baseline and 30 days after procedure | A pulmonary function test that measures the volume and speed of the exhaled air. |
| Primary | Vital Capacity - VC | baseline and 30 days after the procedure | A pulmonary function test that measures the volume and speed of the inhalated and exhaled air. |
| Secondary | Arterial Blood Gases Test - Pa O2 | baseline and 30 days after procedure | presence of oxygen in the blood gases. |
| Secondary | Arterial Blood Gases Test - Pa CO2 | baseline and 30 days after the procedure | presence of CO2 in the arterial blood. |
Source ClinicalTrials.gov
Outcomes5
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Forced Vital Capacity (FVC) | baseline and 30 days after procedure | all patients were evaluated prior and after the procedure | liters | MEAN |
| PRIMARY | Forced Expiratory Volume (FEV1) | baseline and 30 days after procedure | all patients were evaluated prior and after the procedure | liters | MEAN |
| SECONDARY | Arterial Blood Gases Test - Pa O2 | baseline and 30 days after procedure | all patients were evaluated prior and after the procedure. | mmHg | MEAN |
| SECONDARY | Arterial Blood Gases Test - Pa CO2 | baseline and 30 days after the procedure | all patients were evaluated prior and after the procedure | mm Hg | MEAN |
| PRIMARY | Vital Capacity - VC | baseline and 30 days after the procedure | all patients were evaluated prior and after the procedure. | liters | MEAN |
Source ClinicalTrials.gov
Results by group10
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Forced Vital Capacity (FVC) | Prior to the Procedure (Stem Cells Infusion) | 1.5 | Standard Deviation 0.2 | liters | |
| Forced Vital Capacity (FVC) | Post Procedure (Stem Cells Infusion) | 2.1 | Standard Deviation 0.2 | liters | |
| Forced Expiratory Volume (FEV1) | Prior to the Procedure (Stem Cells Infusion) | 0.7 | Standard Deviation 0.1 | liters | |
| Forced Expiratory Volume (FEV1) | Post Procedure (Stem Cells Infusion) | 0.8 | Standard Deviation 0.1 | liters | |
| Arterial Blood Gases Test - Pa O2 | Prior to the Procedure (Stem Cells Infusion) | 69 | Standard Deviation 3 | mmHg | |
| Arterial Blood Gases Test - Pa O2 | Post Procedure (Stem Cells Infusion) | 57 | Standard Deviation 3 | mmHg | |
| Arterial Blood Gases Test - Pa CO2 | Prior to the Procedure (Stem Cells Infusion) | 48.75 | Standard Deviation 2.7 | mm Hg | |
| Arterial Blood Gases Test - Pa CO2 | Post Procedure (Stem Cells Infusion) | 89.25 | Standard Deviation 2.7 | mm Hg | |
| Vital Capacity - VC | Prior to the Procedure (Stem Cells Infusion) | 1.8 | Standard Deviation 0.3 | liters | |
| Vital Capacity - VC | Post Procedure (Stem Cells Infusion) | 1.4 | Standard Deviation 0.3 | liters |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Pre-procedure (Stem Cells Infusion) | STARTED | Prior Then Post Procedure (Stem Cells Infusion) | 4 | |
| Pre-procedure (Stem Cells Infusion) | COMPLETED | Prior Then Post Procedure (Stem Cells Infusion) | 4 | |
| Pre-procedure (Stem Cells Infusion) | NOT COMPLETED | Prior Then Post Procedure (Stem Cells Infusion) | 0 | |
| Post-procedure (Stem Cells Infusion) | STARTED | Prior Then Post Procedure (Stem Cells Infusion) | 4 | |
| Post-procedure (Stem Cells Infusion) | COMPLETED | Prior Then Post Procedure (Stem Cells Infusion) | 4 | |
| Post-procedure (Stem Cells Infusion) | NOT COMPLETED | Prior Then Post Procedure (Stem Cells Infusion) | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Prior Then Post Procedure (Stem Cells Infusion) | ||
| Total, other adverse events | Prior Then Post Procedure (Stem Cells Infusion) | 0 | 4 |
| Total, serious adverse events | Prior Then Post Procedure (Stem Cells Infusion) | 0 | 4 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01110252
GET https://conductscience.org/api/trials/v1/NCT01110252/registered