Trial · NCT01114997
Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
NCT01114997, Phase 4, Terminated, Cedars-Sinai Medical Center; results first posted 2016-06-23
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Lidocaine and Esmolol to Improve the Quality of Recovery. Trials, record NCT01114997. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01114997
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
- NCT number
- NCT01114997
- Status
- Terminated
- Phases
- Phase 4
- Enrollment
- 32 participants, actual
- Lead sponsor
- Cedars-Sinai Medical Center
- Conditions
- Pain, Constipation, Nausea, Vomiting
- Interventions
- Lidocaine, Esmolol, Lidocaine + Esmolol (Combo)
- First posted
- 2010-05-03
- Last updated
- 2016-11-03
- Results first posted
- 2016-06-23
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Post Operative Pain | 1 day | Outcome had a duration of one day at post-anesthesia care unit (PACU) Postoperative pain measured using a Verbal Rating Scale (VRS) Postoperative pain VRS scores: 0 = none pain to 10 = intolerable pain. |
| Primary | Number of Participants With Post Operative Pain One Month After Surgery | 1 month | Highest Post Operative pain one month after surgery, using a verbal rating score from 0 (no pain) to 10 (highest level of pain). Patient received a post-operative follow-up call one month after surgery. |
| Secondary | Opioid Consumption Obtained From the Recorded Data | 1 day | Postoperative use of opioid consumption inside hospital (recorded by study staff and data obtained from patient charts) |
| Secondary | Number of Participants With Postoperative Nausea One Day After Surgery | 1day | Postoperative nausea using a Verbal Rating Scale Outcomes measured at the first day after surgery |
| Secondary | Return to Normal Activities of Daily Living Using Follow up Questionnaires | 1 month | Description: return to normal activities of daily living(including dietary intake, bowel and bladder function, physical activities) |
| Secondary | Patient Satisfaction | 1 month | Patient satisfaction using a verbal rating scale from 0 to 10 0= Not satisfied 10= Excellent |
| Secondary | Post-anesthesia Care Unit (PACU) Stay | 1 day |
Source ClinicalTrials.gov
Outcomes7
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Post Operative Pain | 1 day | Score on a scale | MEAN | |
| PRIMARY | Number of Participants With Post Operative Pain One Month After Surgery | 1 month | Experience of pain at home | participants | NUMBER |
| SECONDARY | Opioid Consumption Obtained From the Recorded Data | 1 day | Opioid: Hydromorphone | mg | MEAN |
| SECONDARY | Number of Participants With Postoperative Nausea One Day After Surgery | 1day | participants | NUMBER | |
| SECONDARY | Return to Normal Activities of Daily Living Using Follow up Questionnaires | 1 month | participants | NUMBER | |
| SECONDARY | Patient Satisfaction | 1 month | Score on a scale | MEAN | |
| SECONDARY | Post-anesthesia Care Unit (PACU) Stay | 1 day | Minutes | MEAN |
Source ClinicalTrials.gov
Results by group21
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Post Operative Pain | Lidocaine | 4 | Standard Deviation 4 | Score on a scale | |
| Post Operative Pain | Esmolol | 2 | Standard Deviation 2 | Score on a scale | |
| Post Operative Pain | Lidocaine + Esmolol (Combo) | 4 | Standard Deviation 3 | Score on a scale | |
| Number of Participants With Post Operative Pain One Month After Surgery | Lidocaine | 10 | participants | ||
| Number of Participants With Post Operative Pain One Month After Surgery | Esmolol | 8 | participants | ||
| Number of Participants With Post Operative Pain One Month After Surgery | Lidocaine + Esmolol (Combo) | 10 | participants | ||
| Opioid Consumption Obtained From the Recorded Data | Lidocaine | 1.5 | Standard Deviation 1 | mg | |
| Opioid Consumption Obtained From the Recorded Data | Esmolol | 1 | Standard Deviation 0.8 | mg | |
| Opioid Consumption Obtained From the Recorded Data | Lidocaine + Esmolol (Combo) | 1.5 | Standard Deviation 1 | mg | |
| Number of Participants With Postoperative Nausea One Day After Surgery | Lidocaine | 3 | participants |
1 to 10 of 21Source ClinicalTrials.gov
See all 21 results by groupParticipant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Lidocaine | 11 | |
| Overall Study | STARTED | Esmolol | 10 | |
| Overall Study | STARTED | Lidocaine + Esmolol (Combo) | 11 | |
| Overall Study | COMPLETED | Lidocaine | 11 | |
| Overall Study | COMPLETED | Esmolol | 10 | |
| Overall Study | COMPLETED | Lidocaine + Esmolol (Combo) | 11 | |
| Overall Study | NOT COMPLETED | Lidocaine | 0 | |
| Overall Study | NOT COMPLETED | Esmolol | 0 | |
| Overall Study | NOT COMPLETED | Lidocaine + Esmolol (Combo) | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Lidocaine | ||
| Total, all-cause mortality | Esmolol | ||
| Total, all-cause mortality | Lidocaine + Esmolol (Combo) | ||
| Total, other adverse events | Lidocaine | 0 | 11 |
| Total, other adverse events | Esmolol | 0 | 10 |
| Total, other adverse events | Lidocaine + Esmolol (Combo) | 0 | 11 |
| Total, serious adverse events | Lidocaine | 0 | 11 |
| Total, serious adverse events | Esmolol | 0 | 10 |
| Total, serious adverse events | Lidocaine + Esmolol (Combo) | 0 | 10 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01114997
GET https://conductscience.org/api/trials/v1/NCT01114997/results?page=2