Trial · NCT01117454

Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia

NCT01117454, Not applicable, Completed, Vanderbilt University Medical Center; results first posted 2017-05-17

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia. Trials, record NCT01117454. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01117454

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia
NCT number: NCT01117454
Status: Completed
Phases: Not applicable
Enrollment: 14 participants, actual
Lead sponsor: Vanderbilt University Medical Center
Conditions: Catecholaminergic Polymorphic Ventricular Tachycardia
Interventions: Flecainide Acetate, Placebo, Beta blocker
First posted: 2010-05-05
Last updated: 2017-06-14
Results first posted: 2017-05-17

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Number of Patients With Ventricular Ectopy or VT During Exercise Treadmill Testing	3 months	Hypothesis: the addition of oral flecainide to standard therapy will reduce ventricular ectopy and/or VT on treadmill exercise treadmill testing in patients with CPVT, compared to placebo plus standard therapy.

Source ClinicalTrials.gov

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Number of Patients With Ventricular Ectopy or VT During Exercise Treadmill Testing	3 months	1 participant did not complete treadmill test	Participants	COUNT_OF_PARTICIPANTS

Source ClinicalTrials.gov

Results by group2

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Category	Value	Spread	Units
Number of Patients With Ventricular Ectopy or VT During Exercise Treadmill Testing	Flecainide		2		Participants
Number of Patients With Ventricular Ectopy or VT During Exercise Treadmill Testing	Placebo		9		Participants

Source ClinicalTrials.gov

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Flecainide Then Placebo	6
Overall Study	STARTED	Placebo Then Flecainide	8
Overall Study	COMPLETED	Flecainide Then Placebo	6
Overall Study	COMPLETED	Placebo Then Flecainide	7
Overall Study	NOT COMPLETED	Flecainide Then Placebo	0
Overall Study	NOT COMPLETED	Placebo Then Flecainide	1

Source ClinicalTrials.gov

Adverse events46

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	Diarrhea	Gastrointestinal disorders	Flecainide	0	13	0
other	Diarrhea	Gastrointestinal disorders	Placebo	1	13	1
other	Headache	Musculoskeletal and connective tissue disorders	Flecainide	1	13	1
other	Headache	Musculoskeletal and connective tissue disorders	Placebo	2	13	3
other	Sinusitis	Infections and infestations	Flecainide	1	13	1
other	Sinusitis	Infections and infestations	Placebo	0	13	0
other	Musculoskelatal Injury	Injury, poisoning and procedural complications	Flecainide	3	13	3
other	Musculoskelatal Injury	Injury, poisoning and procedural complications	Placebo	0	13	0
other	lightheadedness	Nervous system disorders	Flecainide	1	13	1
other	lightheadedness	Nervous system disorders	Placebo	0	13	0

1 to 10 of 46Source ClinicalTrials.gov

See all 46 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Flecainide	0	13
Total, all-cause mortality	Placebo	0	13
Total, other adverse events	Flecainide	11	13
Total, other adverse events	Placebo	6	13
Total, serious adverse events	Flecainide	2	13
Total, serious adverse events	Placebo	2	13

Source ClinicalTrials.gov

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
19330009	BACKGROUND	PubMed
21616285	BACKGROUND	PubMed
28492868	BACKGROUND	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons3

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison	Source
Flecainide vs Placebo: Number of Patients With Ventricular Ectopy or VT During Exercise Treadmill Testing	Trial comparisons
Flecainide vs Placebo: deaths from any cause	Trial comparisons
Flecainide vs Placebo: serious adverse events	Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT01117454

GET https://conductscience.org/api/trials/v1/NCT01117454/events?page=2

API reference For AI assistants