Trial · NCT01125254
Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
NCT01125254, Phase 2, Phase 3, Completed, University of Campinas, Brazil
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major. Trials, record NCT01125254. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01125254
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
- NCT number
- NCT01125254
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 10 participants, actual
- Lead sponsor
- University of Campinas, Brazil
- Conditions
- Thalassemia Major
- Interventions
- Amlodipine
- First posted
- 2010-05-18
- Last updated
- 2015-01-05
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Myocardium T2* | 12 months | Heart T2\* by MRI at 12 months |
| Secondary | Liver T2* | 24 months | Liver T2\* by MRI every 6 months for 2 years. First year with active treatment; second year with withdrawal. |
| Secondary | Heart volumes | 24 months | Diastolic and systolic volumes by MRI every 6 months for 2 years. First year with active treatment; second year with withdrawal. |
| Secondary | Left ventricle ejection fraction | 24 months | LVEF by MRI every 6 months for 2 years. First year with active treatment; second year with withdrawal. |
| Secondary | Serum ferritin | 24 months | Serum ferritin every 6 months for 2 years. First year with active treatment; second year with withdrawal. |
| Secondary | Myocardium T2* | 6-18-24 months | Heart T2\* by MRI every 6 months until 24 months |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 37975597 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01125254
GET https://conductscience.org/api/trials/v1/NCT01125254/registered