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Trial · NCT01134055

Results by group2,234

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Placebo Control Arm QID0.22Standard Error 1.006Letters
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Pazopanib Eye Drops 5 mg/mL TID1.15Standard Error 1.004Letters
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Pazopanib Eye Drops 5 mg/mL QID1.81Standard Error 0.975Letters
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Pazopanib Eye Drops 10 mg/mL BID0.76Standard Error 0.995Letters
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Pazopanib Eye Drops 10 mg/mL TID0.28Standard Error 0.992Letters
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Pazopanib Eye Drops 10 mg/mL QID0.62Standard Error 1.007Letters
Change From Baseline in Best-corrected Visual Acuity (BCVA) as Measured by the Number of Letters Read on the Early Treatment of Diabetic Retinopathy Study (ETDRS) Grading Charts at a Starting Distance of 4 Meters at Week 52
Ranibizumab Injections Active Open-label Control Arm1.42Standard Error 1.020Letters
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPlacebo Control Arm QIDInjection Rate at 28 Weeks65.04Standard Error 3.418Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 5 mg/mL TIDInjection Rate at 28 Weeks55.03Standard Error 3.441Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 5 mg/mL QIDInjection Rate at 28 Weeks67.92Standard Error 3.395Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 10 mg/mL BIDInjection Rate at 28 Weeks66.11Standard Error 3.418Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 10 mg/mL TIDInjection Rate at 28 Weeks61.61Standard Error 3.418Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 10 mg/mL QIDInjection Rate at 28 Weeks59.42Standard Error 3.441Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPlacebo Control Arm QIDOverall Injection Rate at 52 weeks64.24Standard Error 3.263Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 5 mg/mL TIDOverall Injection Rate at 52 weeks55.09Standard Error 3.286Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 5 mg/mL QIDOverall Injection Rate at 52 weeks65.87Standard Error 3.241Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 10 mg/mL BIDOverall Injection Rate at 52 weeks62.50Standard Error 3.263Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 10 mg/mL TIDOverall Injection Rate at 52 weeks64.42Standard Error 3.263Percentage of re-injections
Percentage of Ranibizumab Re-injections Received Over 28 and 52 WeeksPazopanib Eye Drops 10 mg/mL QIDOverall Injection Rate at 52 weeks58.19Standard Error 3.286Percentage of re-injections
Number of Participants With BCVA Over TimePlacebo Control Arm QIDWeek 4, Study Eye / within 5 letters49Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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