Trial · NCT01147042
Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease
NCT01147042, Phase 4, Terminated, National Institute of Allergy and Infectious Diseases (NIAID); results first posted 2017-09-20
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease. Trials, record NCT01147042. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01147042
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease
- NCT number
- NCT01147042
- Status
- Terminated
- Phases
- Phase 4
- Enrollment
- 2 participants, actual
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- Conditions
- IFN-Gamma Therapy, CGD Gene Mutation, CGD Response to IFNg, CGD - Chronic Granulomatous Disease, Immunodeficiency Disease
- Interventions
- IFN-gamma
- First posted
- 2010-06-22
- Last updated
- 2017-09-20
- Results first posted
- 2017-09-20
- Limitations and caveats
- Early termination due to only 2 subjects completing trial.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Basal and PMA-stimulated O2 Production Detected by Ferricytochrome c Reduction in Neutrophils | 21 weeks |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Basal and PMA-stimulated O2 Production Detected by Ferricytochrome c Reduction in Neutrophils | 21 weeks | Data were not collected. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | gp91 CGD With HIGH Baseline Superoxide | 2 | |
| Overall Study | STARTED | Autosomal Recessive CGD With p47 | 0 | |
| Overall Study | COMPLETED | gp91 CGD With HIGH Baseline Superoxide | 2 | |
| Overall Study | COMPLETED | Autosomal Recessive CGD With p47 | 0 | |
| Overall Study | NOT COMPLETED | gp91 CGD With HIGH Baseline Superoxide | 0 | |
| Overall Study | NOT COMPLETED | Autosomal Recessive CGD With p47 | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | gp91 CGD With Relatively High Baseline Superoxide | 0 | 2 |
| Total, other adverse events | gp91 CGD With Relatively High Baseline Superoxide | 0 | 2 |
| Total, serious adverse events | gp91 CGD With Relatively High Baseline Superoxide | 0 | 2 |
Source ClinicalTrials.gov
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01147042
GET https://conductscience.org/api/trials/v1/NCT01147042/registered