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Trial · NCT01154140

Results by group270

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression-Free Survival (PFS) Based on IRRCrizotinib10.995% Confidence Interval 8.3 to 13.9months
Progression-Free Survival (PFS) Based on IRRChemotherapy7.095% Confidence Interval 6.8 to 8.2months
Overall Survival (OS)CrizotinibNA95% Confidence Interval 45.8 to NAmonths
Overall Survival (OS)Chemotherapy47.595% Confidence Interval 32.2 to NAmonths
Overall Survival Probability at Month 12 and 18CrizotinibMonth 1283.595% Confidence Interval 77.0 to 88.3percent probability
Overall Survival Probability at Month 12 and 18ChemotherapyMonth 1278.495% Confidence Interval 71.3 to 83.9percent probability
Overall Survival Probability at Month 12 and 18CrizotinibMonth 1871.595% Confidence Interval 64.0 to 77.7percent probability
Overall Survival Probability at Month 12 and 18ChemotherapyMonth 1866.695% Confidence Interval 58.8 to 73.2percent probability
Objective Response Rate (ORR): Percentage of Participants With Objective Response as Assessed by IRRCrizotinib74.495% Confidence Interval 67.2 to 80.8percentage of participants
Objective Response Rate (ORR): Percentage of Participants With Objective Response as Assessed by IRRChemotherapy45.095% Confidence Interval 37.4 to 52.8percentage of participants
Duration of Response (DR) Based on IRRCrizotinib49.095% Confidence Interval 35.1 to 60.0weeks
Duration of Response (DR) Based on IRRChemotherapy22.995% Confidence Interval 18.0 to 25.1weeks
Time to Tumor Response (TTR) Based on IRRCrizotinib6.1Full Range 2.7 to 41.4weeks
Time to Tumor Response (TTR) Based on IRRChemotherapy12.1Full Range 5.1 to 36.7weeks
Percentage of Participants With Disease Control at Week 12 Based on IRRCrizotinib78.595% Confidence Interval 71.6 to 84.4percentage of participants
Percentage of Participants With Disease Control at Week 12 Based on IRRChemotherapy68.495% Confidence Interval 60.9 to 75.3percentage of participants
Time to Progression (TTP) Based on IRRCrizotinib13.695% Confidence Interval 8.5 to 15.0months
Time to Progression (TTP) Based on IRRChemotherapy7.095% Confidence Interval 6.8 to 8.3months
Time to Intracranial Progression (IC-TTP) Based on IRRCrizotinibNA95% Confidence Interval NA to NAmonths
Time to Intracranial Progression (IC-TTP) Based on IRRChemotherapy17.895% Confidence Interval 13.9 to NAmonths

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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