Trial · NCT01174082
Trial of ID-Specific Donor Vaccinated Lymphocyte Infusion for Patients With Myeloma Relapsing or Failing to Achieve a Complete Remission After an Allogenic Transplant
NCT01174082, Phase 2, Terminated, M.D. Anderson Cancer Center; results first posted 2018-06-01
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Trial of ID-Specific Donor Vaccinated Lymphocyte Infusion for Patients With Myeloma Relapsing or Failing to Achieve a Complete Remission After an Allogenic Transplant. Trials, record NCT01174082. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01174082
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Trial of ID-Specific Donor Vaccinated Lymphocyte Infusion for Patients With Myeloma Relapsing or Failing to Achieve a Complete Remission After an Allogenic Transplant
- NCT number
- NCT01174082
- Status
- Terminated
- Phases
- Phase 2
- Enrollment
- 2 participants, actual
- Lead sponsor
- M.D. Anderson Cancer Center
- Conditions
- Myeloma
- Interventions
- KLH Vaccine, KLH-id Vaccine, GM-CSF, Apheresis, Donor Lymphocyte Infusion (DLI)
- First posted
- 2010-08-03
- Last updated
- 2018-06-01
- Results first posted
- 2018-06-01
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The Rate of Partial Response(PR) and Complete Response(CR) in Patients Receiving DLI From an ID-specific Vaccinated Donor | DLI up to 5 years post DLI | PR defined as 50% reduction disease including serum monoclonal paraprotein and CR defined as absence of original monoclonal paraprotein in serum and urine. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | The Rate of Partial Response(PR) and Complete Response(CR) in Patients Receiving DLI From an ID-specific Vaccinated Donor | DLI up to 5 years post DLI | The donor participant was to supply the cell product to manufacturer the vaccine. The donor has no disease and therefore cannot be analyzed for a response. | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| The Rate of Partial Response(PR) and Complete Response(CR) in Patients Receiving DLI From an ID-specific Vaccinated Donor | Recipient | 1 | Participants | ||
| The Rate of Partial Response(PR) and Complete Response(CR) in Patients Receiving DLI From an ID-specific Vaccinated Donor | Donor | 0 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Recipient | 1 | |
| Overall Study | STARTED | Donor | 1 | |
| Overall Study | COMPLETED | Recipient | 1 | |
| Overall Study | COMPLETED | Donor | 1 | |
| Overall Study | NOT COMPLETED | Recipient | 0 | |
| Overall Study | NOT COMPLETED | Donor | 0 |
Source ClinicalTrials.gov
Adverse events34
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Diarrhea | Gastrointestinal disorders | Recipient | 1 | 1 | |
| other | Diarrhea | Gastrointestinal disorders | Donor | 0 | 1 | |
| other | Infection | Infections and infestations | Recipient | 1 | 1 | |
| other | Infection | Infections and infestations | Donor | 0 | 1 | |
| other | Abd cramping | Gastrointestinal disorders | Recipient | 1 | 1 | |
| other | Abd cramping | Gastrointestinal disorders | Donor | 0 | 1 | |
| other | Insomnia | Nervous system disorders | Recipient | 1 | 1 | |
| other | Insomnia | Nervous system disorders | Donor | 0 | 1 | |
| other | Dizziness | Nervous system disorders | Recipient | 1 | 1 | |
| other | Dizziness | Nervous system disorders | Donor | 0 | 1 |
1 to 10 of 34Source ClinicalTrials.gov
See all 34 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Recipient | 1 | 1 |
| Total, all-cause mortality | Donor | 0 | 1 |
| Total, other adverse events | Recipient | 1 | 1 |
| Total, other adverse events | Donor | 1 | 1 |
| Total, serious adverse events | Recipient | 0 | 1 |
| Total, serious adverse events | Donor | 0 | 1 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Recipient vs Donor: deaths from any cause | Trial comparisons |
| Recipient vs Donor: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01174082
GET https://conductscience.org/api/trials/v1/NCT01174082/events?page=2