Trial · NCT01188863
Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus
NCT01188863, Phase 1, Completed, Lexicon Pharmaceuticals
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus. Trials, record NCT01188863. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01188863
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus
- NCT number
- NCT01188863
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 15 participants, estimated
- Lead sponsor
- Lexicon Pharmaceuticals
- Conditions
- Type 2 Diabetes Mellitus
- Interventions
- 300 mg LX4211 (150 mg tablets), 300 mg LX4211 (50 mg tablets), 300 mg LX4211 (liquid)
- First posted
- 2010-08-26
- Last updated
- 2011-03-30
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Maximum observed plasma concentration | Pharmacokinetics samples collected on day of dosing and 24 and 48 hours post-dose (Follow-up). | |
| Primary | Time at which maximum observed plasma concentration occurs | Pharmacokinetics samples collected on day of dosing and 24 and 48 hours post-dose (Follow-up). | |
| Primary | Half-life of the drug in plasma | Pharmacokinetics samples collected on day of dosing and 24 and 48 hours post-dose (Follow-up). | |
| Secondary | Plasma glucose | Samples collected on initial visit; Day -15 and Day -5 (Washout); numerous timepoints on Day -1 (Washout) and day of dosing; 24 hours post-dose (Follow-up); and upon discharge. | |
| Secondary | Urinary glucose excretion | Samples collected on Day -1 (Washout), day of dosing, and 24 and 48 hours post-dose (Follow-up). | |
| Secondary | Insulin | Samples collected on initial visit; Day -15 and Day -5 (Washout); numerous timepoints on Day -1 (Washout) and day of dosing; 24 hours post-dose (Follow-up); and upon discharge. | |
| Secondary | Peptide YY | Samples collected on initial visit; Day -15 and Day -5 (Washout); numerous timepoints on Day -1 (Washout) and day of dosing; 24 hours post-dose (Follow-up); and upon discharge. | |
| Secondary | Glucagon-like Peptide 1 | Samples collected on initial visit; Day -15 and Day -5 (Washout); numerous timepoints on Day -1 (Washout) and day of dosing; 24 hours post-dose (Follow-up); and upon discharge. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 22739142 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01188863
GET https://conductscience.org/api/trials/v1/NCT01188863/registered