Trial · NCT01190306
Safety Study of the VEGA UV-A System to Treat Keratoconus
NCT01190306, Phase 3, Terminated, Topcon Medical Systems, Inc.; results first posted 2013-03-04
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety Study of the VEGA UV-A System to Treat Keratoconus. Trials, record NCT01190306. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01190306
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety Study of the VEGA UV-A System to Treat Keratoconus
- NCT number
- NCT01190306
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 127 participants, actual
- Lead sponsor
- Topcon Medical Systems, Inc.
- Conditions
- Keratoconus
- Interventions
- The VEGA UV-A Illumination System, Riboflavin
- First posted
- 2010-08-27
- Last updated
- 2022-07-12
- Results first posted
- 2013-03-04
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Corneal Curvature. | 6 Months |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Corneal Curvature. | 6 Months | The CXL-001 study was completed but data analysis was not done. Prior to data analysis, the sponsor, Topcon, decided to terminate the study for administrative reasons only, and not as a result of any safety issues or concerns relating to the study. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | CXL Treatment | 61 | |
| Overall Study | STARTED | Sham Control | 66 | |
| Overall Study | COMPLETED | CXL Treatment | 61 | |
| Overall Study | COMPLETED | Sham Control | 66 | |
| Overall Study | NOT COMPLETED | CXL Treatment | 0 | |
| Overall Study | NOT COMPLETED | Sham Control | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | CXL Treatment | ||
| Total, all-cause mortality | Sham Control | ||
| Total, other adverse events | CXL Treatment | 0 | 61 |
| Total, other adverse events | Sham Control | 0 | 66 |
| Total, serious adverse events | CXL Treatment | 0 | 61 |
| Total, serious adverse events | Sham Control | 0 | 66 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| CXL Treatment vs Sham Control: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01190306
GET https://conductscience.org/api/trials/v1/NCT01190306/registered