Impact of Varying Doses of Amino Acids on Exercise, Muscular and Mental Performance
NCT01215396, Phase 1, Completed, McMaster University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Impact of Varying Doses of Amino Acids on Exercise, Muscular and Mental Performance | ClinicalTrials.gov |
| NCT number | NCT01215396 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Phase 1 | ClinicalTrials.gov |
| Enrollment | 12 participants, actual | ClinicalTrials.gov |
| Lead sponsor | McMaster University | ClinicalTrials.gov |
| Conditions | Psychological Phenomena: Central Fatigue | ClinicalTrials.gov |
| Interventions | AminoVital Amino Acid formulation, Amino Vital Amino Acid formulation, Amino Vital Amino Acid formulation | ClinicalTrials.gov |
| First posted | 2010-10-06 | ClinicalTrials.gov |
| Last updated | 2010-11-02 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Isometric strength test | Two Months | Measured on a Biodex leg extension machine. Subjects performed a 5 second voluntary maximal isometric contraction and peak torque was measured. | ClinicalTrials.gov |
| Primary | Stroop Test | Two months | The Stroop test is a neuropsychological test to discern the subject's reaction time and cognitive processing speed. Subjects completed four subtasks in this test consisting of vocalizing the colour of boxes; random words; congruent word and colour; and incongruent word and colour. | ClinicalTrials.gov |
| Primary | Wing-Kristofferson Two-Model Test | Two months | Subjects will tap their index finger to the beat of a metronome for 10 seconds (synchronization). The metronome will be stopped and the subject will continue tapping for 20 seconds (continuation). | ClinicalTrials.gov |
| Primary | Muscle Damage Markers | Two months | Measurement of serum concentrations of creatine kinase (CK), lactate dehydrogenase (LDH), myoglobin, C-reactive protein (CRP). | ClinicalTrials.gov |
| Secondary | Blood Glucose and Lactate | Two months | Blood glucose was measured by glucose meter from a blood plasma sample. Blood lactate was measured from blood samples aliquoted into perchloric acid. The same is then neutralized and an assay kit is used to measure the lactate concentration. | ClinicalTrials.gov |
| Secondary | Plasma amino acid concentrations | Two months | Using high-performance liquid chromatography, branched chain amino acid concentrations were measured from plasma samples. | ClinicalTrials.gov |
| Secondary | Rating of Perceived Exertion | Two months | Using the Borg Scale, subjects were asked to rate their perceived exertion or how hard they felt they were working on a scale from 6 to 20. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 16
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 7653539 | RESULT | PubMed |
| 7819652 | RESULT | PubMed |
| 8779948 | RESULT | PubMed |
| 8847245 | RESULT | PubMed |
| 9475648 | RESULT | PubMed |
| 11310928 | RESULT | PubMed |
| 11676007 | RESULT | PubMed |
| 15702454 | RESULT | PubMed |
| 16365097 | RESULT | PubMed |
| 16424141 | RESULT | PubMed |
| 16424144 | RESULT | PubMed |
| 17180619 | RESULT | PubMed |
| 17342883 | RESULT | PubMed |
| 17413102 | RESULT | PubMed |
| 18059593 | RESULT | PubMed |
| 18974721 | RESULT | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)