Trial · NCT01216410
Prevention of Intraoperative Nausea and Vomiting During Cesarean Section
NCT01216410, Not applicable, Completed, Duke University; results first posted 2013-03-25
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Prevention of Intraoperative Nausea and Vomiting During Cesarean Section. Trials, record NCT01216410. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01216410
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Prevention of Intraoperative Nausea and Vomiting During Cesarean Section
- NCT number
- NCT01216410
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 306 participants, actual
- Lead sponsor
- Duke University
- Conditions
- Cesarean Delivery
- Interventions
- Metoclopramide, Phenylephrine infusion, Combination Group
- First posted
- 2010-10-07
- Last updated
- 2014-08-06
- Results first posted
- 2013-03-25
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Intraoperative Nausea and Vomiting | Intraoperatively | Comparison of intraoperative nausea and vomiting between the 3 groups. |
| Secondary | Postoperative Nausea and Vomiting (PONV) | 0-2h, 2-6h, 6-24h | |
| Secondary | Pruritus | 0-24 hrs | |
| Secondary | Satisfaction | 24 h | 1=very satisfied, 2=somewhat satisfied, 3= neither satisfied nor dissatisfied, 4=somewhat dissatisfied, 5= very dissatisfied. Number of very satisfied subjects posted. |
| Secondary | Maternal Hemodynamics | Intraoperatively | The number of patients with systolic blood pressure decrease to less than 20 % of baseline intraoperatively |
Source ClinicalTrials.gov
Outcomes5
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Intraoperative Nausea and Vomiting | Intraoperatively | participants | NUMBER | |
| SECONDARY | Postoperative Nausea and Vomiting (PONV) | 0-2h, 2-6h, 6-24h | participants | NUMBER | |
| SECONDARY | Pruritus | 0-24 hrs | participants | NUMBER | |
| SECONDARY | Satisfaction | 24 h | participants | NUMBER | |
| SECONDARY | Maternal Hemodynamics | Intraoperatively | participants with SBP< 20 % baseline | NUMBER |
Source ClinicalTrials.gov
Results by group21
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Intraoperative Nausea and Vomiting | Combination Group | 23 | participants | ||
| Intraoperative Nausea and Vomiting | Metoclopramide | 31 | participants | ||
| Intraoperative Nausea and Vomiting | Phenylephrine Infusion | 49 | participants | ||
| Postoperative Nausea and Vomiting (PONV) | Combination Group | 0-2 hrs PONV | 20 | participants | |
| Postoperative Nausea and Vomiting (PONV) | Metoclopramide | 0-2 hrs PONV | 33 | participants | |
| Postoperative Nausea and Vomiting (PONV) | Phenylephrine Infusion | 0-2 hrs PONV | 39 | participants | |
| Postoperative Nausea and Vomiting (PONV) | Combination Group | 2-6 hrs PONV | 28 | participants | |
| Postoperative Nausea and Vomiting (PONV) | Metoclopramide | 2-6 hrs PONV | 35 | participants | |
| Postoperative Nausea and Vomiting (PONV) | Phenylephrine Infusion | 2-6 hrs PONV | 41 | participants | |
| Postoperative Nausea and Vomiting (PONV) | Combination Group | 6-24 hrs PONV | 22 | participants |
1 to 10 of 21Source ClinicalTrials.gov
See all 21 results by groupParticipant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Combination Group | 103 | |
| Overall Study | STARTED | Metoclopramide | 100 | |
| Overall Study | STARTED | Phenylephrine Infusion | 103 | |
| Overall Study | COMPLETED | Combination Group | 101 | |
| Overall Study | COMPLETED | Metoclopramide | 99 | |
| Overall Study | COMPLETED | Phenylephrine Infusion | 100 | |
| Overall Study | NOT COMPLETED | Combination Group | 2 | |
| Overall Study | NOT COMPLETED | Metoclopramide | 1 | |
| Overall Study | NOT COMPLETED | Phenylephrine Infusion | 3 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Combination Group | ||
| Total, all-cause mortality | Metoclopramide | ||
| Total, all-cause mortality | Phenylephrine Infusion | ||
| Total, other adverse events | Combination Group | 0 | 101 |
| Total, other adverse events | Metoclopramide | 0 | 99 |
| Total, other adverse events | Phenylephrine Infusion | 0 | 100 |
| Total, serious adverse events | Combination Group | 0 | 101 |
| Total, serious adverse events | Metoclopramide | 0 | 99 |
| Total, serious adverse events | Phenylephrine Infusion | 0 | 100 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 23635626 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01216410
GET https://conductscience.org/api/trials/v1/NCT01216410/results?page=2