Trial · NCT01234870
Comprehensive Evaluation of Ischemic Heart Disease Using MRI
NCT01234870, Phase 2, Phase 3, Completed, Northwestern University; results first posted 2014-09-26
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comprehensive Evaluation of Ischemic Heart Disease Using MRI. Trials, record NCT01234870. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01234870
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comprehensive Evaluation of Ischemic Heart Disease Using MRI
- NCT number
- NCT01234870
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 40 participants, actual
- Lead sponsor
- Northwestern University
- Conditions
- Heart Disease, Ischemic, Atherosclerosis, Coronary
- Interventions
- Gadolinium, Adenosine
- First posted
- 2010-11-04
- Last updated
- 2014-09-26
- Results first posted
- 2014-09-26
- Limitations and caveats
The small number of subjects results in reduced statistical power; The cohort was selected from patients at a single medical center, potentially reducing generalizability; Variability in patient behavior during MR scans may affect analyses
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Magnetic Resonance Image Quality Rating | Cross sectional study; magnetic resonance images were obtained on all patients using two different acquisition methods. | The purpose of the study is to assess the incremental value of diagnostic performance using a fully-automated, motion-corrected (MC) first pass myocardial perfusion image acquisition protocol compared to images obtained under a non-corrected, breath-hold, shallow-breathing first pass myocardial perfusion image acquisition protocol in patients with suspected ischemic heart disease. The MR images resulting from two different image acquisition techniques, including Non-Corrected Breath-Hold Shallow-Breathing and Motion-Corrected, were assessed independently by two radiologists (average of 7 years of experience in reading cardiac MRI) using the American Heart Association modified 16 segment model and were evaluated using a four point Likert scale (1 = poor, 2 = fair, 3 = good, and 4 = excellent) for image quality |
| Secondary | Number of Participants With Adverse Events to Demonstrate Feasibility of a Comprehensive Cardiac Magnetic Resonance Imaging Protocol | 14 days | Adverse events relating to administration of adenosine during a coronary heart disease comprehensive cardiac MRI study. |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Magnetic Resonance Image Quality Rating | Cross sectional study; magnetic resonance images were obtained on all patients using two different acquisition methods. | units on a likert scale | MEAN | |
| SECONDARY | Number of Participants With Adverse Events to Demonstrate Feasibility of a Comprehensive Cardiac Magnetic Resonance Imaging Protocol | 14 days | occurances of adverse events | NUMBER |
Source ClinicalTrials.gov
Results by group3
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Magnetic Resonance Image Quality Rating | Ischemic Heart Disease Patients | Motion Corrected Images | 3.57 | Standard Deviation 0.66 | units on a likert scale |
| Magnetic Resonance Image Quality Rating | Ischemic Heart Disease Patients | Non-Corrected Breath-Hold, Shallow-Breathing Image | 2.55 | Standard Deviation 0.81 | units on a likert scale |
| Number of Participants With Adverse Events to Demonstrate Feasibility of a Comprehensive Cardiac Magnetic Resonance Imaging Protocol | Adenosine | 0 | occurances of adverse events |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Ischemic Heart Disease Patients | 40 | |
| Overall Study | COMPLETED | Ischemic Heart Disease Patients | 40 | |
| Overall Study | NOT COMPLETED | Ischemic Heart Disease Patients | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Adenosine | ||
| Total, other adverse events | Adenosine | 0 | 40 |
| Total, serious adverse events | Adenosine | 0 | 40 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01234870
GET https://conductscience.org/api/trials/v1/NCT01234870/registered