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Trial · NCT01243424

Results by group58

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
The First 3-point Major Adverse Cardiovascular Events (3P-MACE)Linagliptin20.7Events/ 1000 patients-years
The First 3-point Major Adverse Cardiovascular Events (3P-MACE)Glimepiride21.2Events/ 1000 patients-years
The First 4-point (4P)- MACELinagliptin23.4Events/ 1000 patients-years
The First 4-point (4P)- MACEGlimepiride23.7Events/ 1000 patients-years
Percentage of Participants Taking Trial Medication at Trial End, Maintained Glycaemic Control (HbA1c ≤7.0%) Without Need for Rescue Medication, Without >2% Weight Gain, and Without Moderate/Severe Hypoglycaemic Episodes During Maintenance Phase
Linagliptin16.095% Confidence Interval 14.7 to 17.3Percentage of participants (%)
Percentage of Participants Taking Trial Medication at Trial End, Maintained Glycaemic Control (HbA1c ≤7.0%) Without Need for Rescue Medication, Without >2% Weight Gain, and Without Moderate/Severe Hypoglycaemic Episodes During Maintenance Phase
Glimepiride10.295% Confidence Interval 9.1 to 11.3Percentage of participants (%)
Percentage of Participants Who Were on Trial Medication at Trial End, Maintained Glycaemic Control (HbA1c ≤7.0%) Without Need for Rescue Medication, and Without >2% Weight Gain During Maintenance Phase
Linagliptin17.495% Confidence Interval 16.1 to 18.8Percentage of participants (%)
Percentage of Participants Who Were on Trial Medication at Trial End, Maintained Glycaemic Control (HbA1c ≤7.0%) Without Need for Rescue Medication, and Without >2% Weight Gain During Maintenance Phase
Glimepiride14.195% Confidence Interval 12.9 to 15.4Percentage of participants (%)
Percentage of Participants With the Occurrence of at Least One Event of 3P-MACELinagliptin11.895% Confidence Interval 10.7 to 13.0Percentage of participants (%)
Percentage of Participants With the Occurrence of at Least One Event of 3P-MACEGlimepiride12.095% Confidence Interval 10.9 to 13.2Percentage of participants (%)
Percentage of Participants With the Occurrence of at Least One Event of 4P -MACELinagliptin13.295% Confidence Interval 12.0 to 14.4Percentage of participants (%)
Percentage of Participants With the Occurrence of at Least One Event of 4P -MACEGlimepiride13.395% Confidence Interval 12.2 to 14.6Percentage of participants (%)
Percentage of Participants With Occurrence of Any of the Components of the Composite Endpoint of All Adjudication-confirmed EventsLinagliptin17.195% Confidence Interval 15.8 to 18.5Percentage of participants (%)
Percentage of Participants With Occurrence of Any of the Components of the Composite Endpoint of All Adjudication-confirmed EventsGlimepiride17.895% Confidence Interval 16.4 to 19.2Percentage of participants (%)
Time to First Occurrence of Any of the Components of the Composite Endpoint of All Adjudication-confirmed EventsLinagliptin31.1Events/ 1000 patients-years
Time to First Occurrence of Any of the Components of the Composite Endpoint of All Adjudication-confirmed EventsGlimepiride32.4Events/ 1000 patients-years
Change From Baseline to Final Visit in Hemoglobin A1c (HbA1c)Linagliptin0.06Standard Error 0.02Percentage glycosylated hemoglobin (%)
Change From Baseline to Final Visit in Hemoglobin A1c (HbA1c)Glimepiride0.15Standard Error 0.02Percentage glycosylated hemoglobin (%)
Change From Baseline to Final Visit in Fasting Plasma Glucose (FPG)Linagliptin12.4Standard Error 0.9Milligram/ deciliter (mg/dL)
Change From Baseline to Final Visit in Fasting Plasma Glucose (FPG)Glimepiride19.7Standard Error 0.9Milligram/ deciliter (mg/dL)

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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