Trial · NCT01269749
Radioactive Iodide Therapy for Pediatric Graves' Disease
NCT01269749, Phase 2, Completed, University of Florida; results first posted 2017-11-06
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Radioactive Iodide Therapy for Pediatric Graves' Disease. Trials, record NCT01269749. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01269749
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Radioactive Iodide Therapy for Pediatric Graves' Disease
- NCT number
- NCT01269749
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 19 participants, actual
- Lead sponsor
- University of Florida
- Conditions
- Graves' Disease
- Interventions
- RAI treatment, ATD Group
- First posted
- 2011-01-04
- Last updated
- 2017-11-06
- Results first posted
- 2017-11-06
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Dosimetry Studies | 4 years | Primary Aims. We propose to (1) perform dosimetry to assess whole body radiation exposure following 131II therapy in children treated for GD; and (2) assess the effects of 131I treatment of GD (treated with medication or surgery) on chromosome translocations. |
| Secondary | Cancer Risk Assessment | 4 years | Secondary Aims. (i) As a follow-up to the first primary aim, we will calculate potential cancer risk from the radiation exposure data; and (ii) within the analyses for the second primary aim, we will evaluate chromosomal translocation in children treated with 131I vs. not, as related to age and dose of 131I. |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Dosimetry Studies | 4 years | Data was not collected | ||
| SECONDARY | Cancer Risk Assessment | 4 years | Data was not collected |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | RAI Treatment | 16 | |
| Overall Study | STARTED | ATD Group | 3 | |
| Overall Study | COMPLETED | RAI Treatment | 16 | |
| Overall Study | COMPLETED | ATD Group | 3 | |
| Overall Study | NOT COMPLETED | RAI Treatment | 0 | |
| Overall Study | NOT COMPLETED | ATD Group | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | RAI Treatment | 0 | 16 |
| Total, all-cause mortality | ATD Group | 0 | 3 |
| Total, other adverse events | RAI Treatment | 0 | 16 |
| Total, other adverse events | ATD Group | 0 | 3 |
| Total, serious adverse events | RAI Treatment | 0 | 16 |
| Total, serious adverse events | ATD Group | 0 | 3 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01FD003707 | Radioactive Iodide Therapy of Pediatric Graves' Disease | RIVKEES, SCOTT A. | UNIVERSITY OF FLORIDA | FOOD AND DRUG ADMINISTRATION | 2010 to 2015 |
Source NIH RePORTER
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| RAI Treatment vs ATD Group: deaths from any cause | Trial comparisons |
| RAI Treatment vs ATD Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01269749
GET https://conductscience.org/api/trials/v1/NCT01269749/registered