Trial · NCT01271114
Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension
NCT01271114, Phase 3, Terminated, Hospital General de Ciudad Real
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension. Trials, record NCT01271114. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01271114
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension
- NCT number
- NCT01271114
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 21 participants, actual
- Lead sponsor
- Hospital General de Ciudad Real
- Conditions
- Septic Shock, Sepsis-associated Hypotension
- Interventions
- Hypertonic Saline and Terlipressin, Normal saline and norepinephrine
- First posted
- 2011-01-06
- Last updated
- 2014-03-10
- Other registries' IDs
- eudract:2010-024138-43
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | MOD (Multiple Organ Dysfunction) Score | daily, as long as the patient stays in the ICU | |
| Secondary | Hypertonic Saline restores IV fluid response parameters (Pulse Pressure Variation or Systolic Volume Variation) adequately | First 48 hours | |
| Secondary | Hypertonic Saline associated with terlipressin maintains plasma sodium levels 130-155mEq/L | As long as Hypertonic saline plus terlipressin are in use and one week later | |
| Secondary | There is an inverse relationship between plasma sodium and plasma procalcitonin levels measured by a negative Pearson coefficient | As long as the patient stays in the ICU | |
| Secondary | Hypertonic Saline associated with terlipressin normalizes blood pressure in septic shock | First 48 hours | |
| Secondary | Hypertonic Saline boluses increases plasma levels of vasopressin (AVP) | First week in ICU | |
| Secondary | Hypertonic Saline use rises levels of cortisol but not of adrenocorticotropic hormone (ACTH) | First week in ICU |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01271114
GET https://conductscience.org/api/trials/v1/NCT01271114/registered