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A Study to Investigate the Long-term Safety and Efficacy of Tolvaptan in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Trial 156-04-251 in Japan]
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Trial · NCT01280721

Adverse events118

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

101 to 118 of 118

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TypeEventOrgan systemGroupAffectedAt riskEvents
seriousHepatic cyst infectionInfections and infestationsTolvaptan1135
seriousLigament ruptureInjury, poisoning and procedural complicationsTolvaptan1135
seriousNasopharyngitisInfections and infestationsTolvaptan1135
seriousSpinal column injuryInjury, poisoning and procedural complicationsTolvaptan1135
seriousHand fractureInjury, poisoning and procedural complicationsTolvaptan1135
seriousJoint dislocationsInjury, poisoning and procedural complicationsTolvaptan1135
seriousSpondylolisthesisMusculoskeletal and connective tissue disordersTolvaptan1135
seriousUterine leiomyomaNeoplasms benign, malignant and unspecified (incl cysts and polyps)Tolvaptan1135
seriousAcute monocytic leukaemiaNeoplasms benign, malignant and unspecified (incl cysts and polyps)Tolvaptan1135
seriousOvarian cancerNeoplasms benign, malignant and unspecified (incl cysts and polyps)Tolvaptan1135
seriousUterine cancerNeoplasms benign, malignant and unspecified (incl cysts and polyps)Tolvaptan1135
seriousSubarachnoid haemorrhageNervous system disordersTolvaptan1135
seriousDizzinessNervous system disordersTolvaptan1135
seriousIntracranial aneurysmNervous system disordersTolvaptan1135
seriousGestational hypertensionPregnancy, puerperium and perinatal conditionsTolvaptan1135
seriousRenal painRenal and urinary disordersTolvaptan1135
seriousRenal cyst haemorrhageRenal and urinary disordersTolvaptan2135
seriousRenal cyst rupturedRenal and urinary disordersTolvaptan1135

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT01280721/events?page=6

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