Trial · NCT01290146
ELEVATE Early LEvosimendan Vs Usual Care in Advanced Chronic hearT failurE
NCT01290146, Phase 3, Terminated, Niguarda Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. ELEVATE Early LEvosimendan Vs Usual Care in Advanced Chronic hearT failurE. Trials, record NCT01290146. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01290146
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- ELEVATE Early LEvosimendan Vs Usual Care in Advanced Chronic hearT failurE
- NCT number
- NCT01290146
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 13 participants, actual
- Lead sponsor
- Niguarda Hospital
- Conditions
- Advanced Chronic Heart Failure
- Interventions
- Diuretics, Levosimendan
- First posted
- 2011-02-04
- Last updated
- 2017-04-10
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of days alive free of Transplant and out-of-hospital (DAOH) | Measured at 12 months | |
| Secondary | Incidence of acute renal dysfunction | Measured at at 24 hours since inception of randomized treatment for acute worsening HF | proportion of subjects who develop AKIN stage 1 (increase \> 0.3 mg/dl or \> 25% in serum creatinine from previous visit) |
| Secondary | All cause mortality, hospital readmission and unscheduled office and emergency department visits for ADCHF | Measured at 12 months | A combination of all cause hospital admissions/death/urgent heart transplantation/LV assist device implantation |
| Secondary | BNP changes | Measured at at end-of- study and at each eventual destabilization | Percent changes in BNP vs baseline |
| Secondary | Number of hospital admissions for acute worsening HF | Measured at 12 months | Number of hospital admissions for acute worsening HF |
| Secondary | Costs | Measured at 12 months | Direct health care costs for days in hospital, supplementary visits, drug treatment |
| Secondary | Treatment-related adverse events | Measured at 12 months | death, hospital a dimission, emergency room or clinic unscheduled visits |
| Secondary | Adverse changes in blood pressure or heart rate | Measured at 24 hours after iv treatment | Hypotension (\< 90 mmHg), tachycardia (\> 110 bpm) |
| Secondary | ECG changes | Measured at 24 hours after iv treatment | Rhythm, rate, conduction disturbances, ventricular arrhythmias, repolarization changes |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01290146
GET https://conductscience.org/api/trials/v1/NCT01290146/registered