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Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity
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Trial · NCT01351753

Results by group24

Each measurement the trial posted, group by group, in the words and numbers it posted.

1 to 20 of 24

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OutcomeGroupCategoryValueSpreadUnits
Weight (Percent Change From Baseline)Metformin-10.995% Confidence Interval -14.4 to -7.2percentage of weight change
Weight (Percent Change From Baseline)Metformin + Orlistat-10.595% Confidence Interval -14.0 to -6.9percentage of weight change
Weight (Percent Change From Baseline)Metformin + Topiramate-14.095% Confidence Interval -17.3 to -10.5percentage of weight change
Weight (Percent Change From Baseline)Topiramate-12.295% Confidence Interval -15.6 to -8.6percentage of weight change
Weight (Percent Change From Baseline)Metformin + Topiramate + Orlistat-16.795% Confidence Interval -20.3 to -13.0percentage of weight change
Weight (Percent Change From Baseline)Placebo-6.795% Confidence Interval -10.5 to -2.7percentage of weight change
Office Systolic Blood Pressure (mmHg Change From Baseline)Metformin-11.4295% Confidence Interval -21.10 to -1.74mmHg
Office Systolic Blood Pressure (mmHg Change From Baseline)Metformin + Orlistat-11.4195% Confidence Interval -20.88 to -1.94mmHg
Office Systolic Blood Pressure (mmHg Change From Baseline)Metformin + Topiramate-10.3395% Confidence Interval -19.52 to -1.14mmHg
Office Systolic Blood Pressure (mmHg Change From Baseline)Topiramate-8.5595% Confidence Interval -18.53 to 1.44mmHg
Office Systolic Blood Pressure (mmHg Change From Baseline)Metformin + Topiramate + Orlistat-14.4795% Confidence Interval -24.87 to -4.08mmHg
Office Systolic Blood Pressure (mmHg Change From Baseline)Placebo-13.2695% Confidence Interval -23.28 to -3.23mmHg
Centimeter Change in Waist CircumferenceMetformin-10.6295% Confidence Interval -20.48 to -0.77cm change
Centimeter Change in Waist CircumferenceMetformin + Orlistat-9.0495% Confidence Interval -18.78 to -0.78cm change
Centimeter Change in Waist CircumferenceMetformin + Topiramate-11.6595% Confidence Interval -21.20 to -2.11cm change
Centimeter Change in Waist CircumferenceTopiramate-16.6395% Confidence Interval -26.59 to -6.66cm change
Centimeter Change in Waist CircumferenceMetformin + Topiramate + Orlistat-15.7695% Confidence Interval -26.44 to -5.08cm change
Centimeter Change in Waist CircumferencePlacebo-10.7895% Confidence Interval -20.79 to -0.78cm change
Carotid-femoral Pulse Wave Velocity (PWV)(Change After 6 Months From Baseline)Metformin-1.0995% Confidence Interval -2.96 to 0.78meters/sec
Carotid-femoral Pulse Wave Velocity (PWV)(Change After 6 Months From Baseline)Metformin + Orlistat-1.5695% Confidence Interval -3.47 to 0.36meters/sec

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT01351753/results

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