Trial · NCT01390181
The Effect of Losartan in Bicuspid Aortic Valve Patients
NCT01390181, Not applicable, Terminated, University of Michigan; results first posted 2017-04-14
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Effect of Losartan in Bicuspid Aortic Valve Patients. Trials, record NCT01390181. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01390181
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Effect of Losartan in Bicuspid Aortic Valve Patients
- NCT number
- NCT01390181
- Status
- Terminated
- Phases
- Not applicable
- Enrollment
- 4 participants, actual
- Lead sponsor
- University of Michigan
- Conditions
- Bicuspid Aortic Valve, Thoracic Aortic Aneurysm
- Interventions
- Cozaar
- First posted
- 2011-07-08
- Last updated
- 2017-04-14
- Results first posted
- 2017-04-14
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Inflammatory Markers Levels | Baseline and 12 months | Changes in levels of Matrix Metalloproteinase (MMP-2, MMP-9), Tissue Inhibitor of Metalloproteinases (TIMP 1, TIMP 2), \& Transforming Growth Factor-Beta (TGFB) in circulation while taking medication from baseline at 3 months, 6 months and 12 months. The 12 month levels were the primary outcome. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Inflammatory Markers Levels | Baseline and 12 months | No participants were analyzed because the study terminated prior to data collection for final primary outcome measure. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Losartan | 4 | |
| Overall Study | COMPLETED | Losartan | 0 | |
| Overall Study | NOT COMPLETED | Losartan | 4 |
Source ClinicalTrials.gov
Adverse events5
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Increase in Blood Pressure | Cardiac disorders | Losartan | 1 | 4 | 1 |
| other | Shingles | Nervous system disorders | Losartan | 1 | 4 | 1 |
| other | Cardiace Disorder | Cardiac disorders | Losartan | 1 | 4 | 1 |
| other | Fatigue | General disorders | Losartan | 1 | 4 | 1 |
| other | Fall | Musculoskeletal and connective tissue disorders | Losartan | 1 | 4 | 1 |
Source ClinicalTrials.gov
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Losartan | ||
| Total, other adverse events | Losartan | 2 | 4 |
| Total, serious adverse events | Losartan | 0 | 4 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01390181
GET https://conductscience.org/api/trials/v1/NCT01390181/registered