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Trial · NCT01428453

Results by group30

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline (Day 0) in Cerebral Spinal Fluid (CSF) Amyloid Beta Peptide (Abeta) 42 and Abeta40 at Week 24Placebo Once DailyAbeta42-6.3Standard Error 18.10Nanograms per Liter
Change From Baseline (Day 0) in Cerebral Spinal Fluid (CSF) Amyloid Beta Peptide (Abeta) 42 and Abeta40 at Week 24Rilapladib 250 mg Once DailyAbeta4233.6Standard Error 19.02Nanograms per Liter
Change From Baseline (Day 0) in Cerebral Spinal Fluid (CSF) Amyloid Beta Peptide (Abeta) 42 and Abeta40 at Week 24Placebo Once DailyAbeta40-77.4Standard Error 181.33Nanograms per Liter
Change From Baseline (Day 0) in Cerebral Spinal Fluid (CSF) Amyloid Beta Peptide (Abeta) 42 and Abeta40 at Week 24Rilapladib 250 mg Once DailyAbeta40-327.7Standard Error 190.56Nanograms per Liter
Change From Baseline (Day 0) in CSF Abeta42/ Abeta40 Ratio at Week 24Placebo Once Daily0.002Standard Error 0.0068Ratio
Change From Baseline (Day 0) in CSF Abeta42/ Abeta40 Ratio at Week 24Rilapladib 250 mg Once Daily0.018Standard Error 0.0071Ratio
Change From Baseline (Day 0) in CSF Tau and Phosphorylated Tau (P-tau) Measures at Week 24Placebo Once DailyCSF tau38.2Standard Error 29.98Nanograms per Liter
Change From Baseline (Day 0) in CSF Tau and Phosphorylated Tau (P-tau) Measures at Week 24Rilapladib 250 mg Once DailyCSF tau-18.8Standard Error 31.90Nanograms per Liter
Change From Baseline (Day 0) in CSF Tau and Phosphorylated Tau (P-tau) Measures at Week 24Placebo Once DailyP-tau1.3Standard Error 1.67Nanograms per Liter
Change From Baseline (Day 0) in CSF Tau and Phosphorylated Tau (P-tau) Measures at Week 24Rilapladib 250 mg Once DailyP-tau-1.7Standard Error 1.76Nanograms per Liter
Change From Baseline (Day 0) in the Computerized Test Battery for Cognition (CogState) Battery Working Memory/Executive Function (WM/EF) Composite Score at Week 24Placebo Once Daily-0.150Standard Error 0.0501Scores on a scale
Change From Baseline (Day 0) in the Computerized Test Battery for Cognition (CogState) Battery Working Memory/Executive Function (WM/EF) Composite Score at Week 24Rilapladib 250 mg Once Daily0.016Standard Error 0.0538Scores on a scale
Change From Baseline (Day 0) in CSF Albumin Quotients at Week 24Placebo Once Daily0.11Standard Error 0.172Nanograms per Liter
Change From Baseline (Day 0) in CSF Albumin Quotients at Week 24Rilapladib 250 mg Once Daily-0.13Standard Error 0.184Nanograms per Liter
Change From Baseline (Day 0) in Plasma Levels of Abeta42 and Abeta40 at Week 24Placebo Once DailyAbeta421.5Standard Error 0.90Nanograms per Liter
Change From Baseline (Day 0) in Plasma Levels of Abeta42 and Abeta40 at Week 24Rilapladib 250 mg Once DailyAbeta420.2Standard Error 0.94Nanograms per Liter
Change From Baseline (Day 0) in Plasma Levels of Abeta42 and Abeta40 at Week 24Placebo Once DailyAbeta408.8Standard Error 3.91Nanograms per Liter
Change From Baseline (Day 0) in Plasma Levels of Abeta42 and Abeta40 at Week 24Rilapladib 250 mg Once DailyAbeta409.7Standard Error 4.06Nanograms per Liter
Change From Baseline (Day 0) in Plasma Levels of Abeta42/Abeta40 Ratio at Week 24Placebo Once Daily-0.010Standard Error 0.0045Ratio
Change From Baseline (Day 0) in Plasma Levels of Abeta42/Abeta40 Ratio at Week 24Rilapladib 250 mg Once Daily-0.012Standard Error 0.0047Ratio

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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