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Trial · NCT01431521

Results by group15

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Hepatic FatMK-4074-35.7395% Confidence Interval -44.53 to -26.93Percent change
Percent Change From Baseline in Hepatic FatPioglitazone-18.0495% Confidence Interval -26.84 to -9.24Percent change
Percent Change From Baseline in Hepatic FatPlacebo8.6395% Confidence Interval -0.17 to 17.43Percent change
Percent Change From Baseline in Alanine Transaminase (ALT)MK-4074-9.8295% Confidence Interval -21.13 to 1.49Percent change
Percent Change From Baseline in Alanine Transaminase (ALT)Pioglitazone-20.2195% Confidence Interval -31.52 to -8.90Percent change
Percent Change From Baseline in Alanine Transaminase (ALT)Placebo-3.4795% Confidence Interval -15.08 to 8.13Percent change
Percent Change From Baseline Aspartate Transaminase (AST)MK-4074-6.7495% Confidence Interval -19.73 to 6.24Percent change
Percent Change From Baseline Aspartate Transaminase (AST)Pioglitazone-13.9595% Confidence Interval -26.93 to -0.97Percent change
Percent Change From Baseline Aspartate Transaminase (AST)Placebo-3.2895% Confidence Interval -16.64 to 10.08Percent change
Number of Participants Experiencing One or More Adverse Events (AE)MK-40744Participants
Number of Participants Experiencing One or More Adverse Events (AE)Pioglitazone4Participants
Number of Participants Experiencing One or More Adverse Events (AE)Placebo5Participants
Number of Participants Who Discontinued Study Drug Due to an AEMK-40740Participants
Number of Participants Who Discontinued Study Drug Due to an AEPioglitazone0Participants
Number of Participants Who Discontinued Study Drug Due to an AEPlacebo0Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT01431521/results