Trial · NCT01439308
Intranasal SB-705498 in Non-allergic Rhinitis Patients
NCT01439308, Phase 2, Completed, GlaxoSmithKline
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Intranasal SB-705498 in Non-allergic Rhinitis Patients. Trials, record NCT01439308. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01439308
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Intranasal SB-705498 in Non-allergic Rhinitis Patients
- NCT number
- NCT01439308
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 40 participants, actual
- Lead sponsor
- GlaxoSmithKline
- Conditions
- Rhinitis
- Interventions
- Placebo, SB-705498
- First posted
- 2011-09-23
- Last updated
- 2016-12-01
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Assessment of total symptom score (TSS) after unilateral, incremental dose, intranasal challenge with capsaicin | 0-4hours following dosing | |
| Primary | Assessment of total Ipsilateral secretion's weight after unilateral, incremental dose, intranasal challenge with capsaicin | 0-4hours following dosing | |
| Secondary | Change from baseline in peak nasal inspiratory flow (PNIF) after unilateral, incremental dose, intranasal challenge with capsaicin | 0-4hours following dosing | |
| Secondary | Assessment of Total Contralateral secretion's weight after unilateral, incremental dose, intranasal challenge with capsaicin | 0-4hours following dosing | |
| Secondary | Number of participants with Individual Symptoms as assessed by TSS components after unilateral, incremental dose, intranasal challenge with capsaicin | 0-4hours | |
| Secondary | Soluble biochemical mediators, including but not limited to neuropeptides, in nasal secretions induced after unilateral, incremental dose, intranasal challenge with capsaicin | 0-4hours following dosing | |
| Secondary | Intranasal, single dose SB-705498 plasma PK parameters-Cmax | 0-4hours | |
| Secondary | Intranasal, single dose SB-705498 plasma PK parameters- Tmax | 0-4hours post dosing | |
| Secondary | Intranasal, single dose SB-705498 plasma PK parameters- AUC(0-t) | 0-4hours post dosing | |
| Secondary | Number of participants with adverse events | Day 1 |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01439308
GET https://conductscience.org/api/trials/v1/NCT01439308/registered