Trial · NCT01460225
Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation
NCT01460225, Phase 4, Completed, Dartmouth-Hitchcock Medical Center; results first posted 2018-07-13
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation. Trials, record NCT01460225. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01460225
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation
- NCT number
- NCT01460225
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 19 participants, actual
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- lubiprostone
- First posted
- 2011-10-26
- Last updated
- 2018-07-13
- Results first posted
- 2018-07-13
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Gastric Emptying | Day 1 and Day 7 | gastric emptying was measured before and after 7 days of treatment.at set times (2 and 4 hours post eating a radio-labeled meal) |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Gastric Emptying | Day 1 and Day 7 | percent meal retention | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Gastric Emptying | Prior to Treatement With Lubiprostone | 2 Hours after meal | 0.27 | Standard Deviation NA | percent meal retention |
| Gastric Emptying | Post Treatment With Lubiprostone | 2 Hours after meal | 0.384 | Standard Deviation NA | percent meal retention |
| Gastric Emptying | Prior to Treatement With Lubiprostone | 4 Hours after meal | 0.04 | Standard Deviation NA | percent meal retention |
| Gastric Emptying | Post Treatment With Lubiprostone | 4 Hours after meal | 0.051 | Standard Deviation NA | percent meal retention |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Lubirprostone | 19 | |
| Overall Study | COMPLETED | Lubirprostone | 19 | |
| Overall Study | NOT COMPLETED | Lubirprostone | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | nausea | Gastrointestinal disorders | All- Single Arm | 2 | 19 | 2 |
| other | Headache | General disorders | All- Single Arm | 1 | 19 | 1 |
Source ClinicalTrials.gov
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | All- Single Arm | 0 | 19 |
| Total, other adverse events | All- Single Arm | 2 | 19 |
| Total, serious adverse events | All- Single Arm | 0 | 19 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01460225
GET https://conductscience.org/api/trials/v1/NCT01460225/registered