Trial · NCT01487083
A Long-Term Safety Study of Pomaglumetad Methionil in Schizophrenia
NCT01487083, Phase 3, Terminated, Denovo Biopharma LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Long-Term Safety Study of Pomaglumetad Methionil in Schizophrenia. Trials, record NCT01487083. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01487083
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Long-Term Safety Study of Pomaglumetad Methionil in Schizophrenia
- NCT number
- NCT01487083
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 129 participants, actual
- Lead sponsor
- Denovo Biopharma LLC
- Conditions
- Schizophrenia
- Interventions
- Pomaglumetad methionil
- First posted
- 2011-12-07
- Last updated
- 2026-09-14
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Categorical change from baseline up to 5 years in Barnes Akathisia Scale (BAS) | Baseline, up to 5 years | |
| Primary | Categorical change from baseline up to 5 years in Simpson-Angus Scale (SAS) | Baseline, up to 5 years | |
| Primary | Categorical change from baseline up to 5 years in Abnormal Involuntary Movement Scale (AIMS) | Baseline, up to 5 years | |
| Primary | Proportion of participants with clinically significant weight change from baseline up to 5 years | Baseline up to 5 years | |
| Primary | Categorical change from baseline up to 5 years in prolactin level | Baseline, up to 5 years | |
| Primary | Categorical change from baseline up to 5 years in fasting glucose and lipids | Baseline, up to 5 years | |
| Secondary | Time to lack of efficacy | Baseline up to 5 years | |
| Secondary | Number of participants with suicidal behaviors and ideations measured by Columbia Suicide Severity Rating Scale (CSSRS) | Baseline up to 5 years | |
| Secondary | Change from baseline up to 5 years in Clinical Global Impressions-Severity (CGI-S) | Baseline, up to 5 years | |
| Secondary | Change from baseline up to 5 years in Brief Psychiatric Rater Scale (BPRS) | Baseline, up to 5 years |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01487083
GET https://conductscience.org/api/trials/v1/NCT01487083/registered