Trial · NCT01495481
Dexmedetomidine and Adenosine: Therapeutic Use for SVT
NCT01495481, Not applicable, Completed, University of Pittsburgh; results first posted 2017-03-28
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Dexmedetomidine and Adenosine: Therapeutic Use for SVT. Trials, record NCT01495481. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01495481
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Dexmedetomidine and Adenosine: Therapeutic Use for SVT
- NCT number
- NCT01495481
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 22 participants, actual
- Lead sponsor
- University of Pittsburgh
- Conditions
- Supraventricular Tachycardia
- Interventions
- Dexmedetomidine, Adenosine
- First posted
- 2011-12-20
- Last updated
- 2017-03-28
- Results first posted
- 2017-03-28
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Termination of SVT | Within 3 minutes | Number of participants with SVT Termination within 3 minutes of medication administration |
| Secondary | Number of Participants With Sinus Pause >2.5 Sec After Termination of SVT | 1 minute | Evaluation of the number of participants with sinus pause \> 2.5 sec, after dexmedetomidine vs. adenosine induced SVT termination |
| Secondary | Number of Participants With Tachyarrhythmias After Medication Administration | 10 minutes | Number of participants with tachyarrhythmias, including Ventricular (Ventricular Tachycardia \& Fibrillation)and supraventricular (Atrial Flutter \& Fibrillation) after dexmedetomidine vs. adenosine administration |
| Secondary | Number of Participants With Hypotension by Non-invasive Cuff in First 10 Minutes After Medication Administration | 10 minutes | Blood pressure changes after dexmedetomidine vs. adenosine. Blood pressure measured by non-invasive cuff prior to medication administration, and then at 1 min, 3 min, 5 min after medication administration. Number of participants with a significant drop in blood pressure (mmHg) compared to baseline would be counted for hypotension. |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Termination of SVT | Within 3 minutes | participants | NUMBER | |
| SECONDARY | Number of Participants With Sinus Pause >2.5 Sec After Termination of SVT | 1 minute | participants | NUMBER | |
| SECONDARY | Number of Participants With Tachyarrhythmias After Medication Administration | 10 minutes | participants | NUMBER | |
| SECONDARY | Number of Participants With Hypotension by Non-invasive Cuff in First 10 Minutes After Medication Administration | 10 minutes | participants | NUMBER |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Termination of SVT | Dexmedetomidine | 16 | participants | ||
| Termination of SVT | Adenosine | 21 | participants | ||
| Number of Participants With Sinus Pause >2.5 Sec After Termination of SVT | Dexmedetomidine | 0 | participants | ||
| Number of Participants With Sinus Pause >2.5 Sec After Termination of SVT | Adenosine | 16 | participants | ||
| Number of Participants With Tachyarrhythmias After Medication Administration | Dexmedetomidine | 0 | participants | ||
| Number of Participants With Tachyarrhythmias After Medication Administration | Adenosine | 0 | participants | ||
| Number of Participants With Hypotension by Non-invasive Cuff in First 10 Minutes After Medication Administration | Dexmedetomidine | 1 | participants | ||
| Number of Participants With Hypotension by Non-invasive Cuff in First 10 Minutes After Medication Administration | Adenosine | 0 | participants |
Source ClinicalTrials.gov
Participant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Adenosine | STARTED | Adenosine and Dexmedetomidine | 22 | |
| Adenosine | COMPLETED | Adenosine and Dexmedetomidine | 22 | |
| Adenosine | NOT COMPLETED | Adenosine and Dexmedetomidine | 0 | |
| Washout | STARTED | Adenosine and Dexmedetomidine | 22 | |
| Washout | COMPLETED | Adenosine and Dexmedetomidine | 22 | |
| Washout | NOT COMPLETED | Adenosine and Dexmedetomidine | 0 | |
| Dexmedetomidine | STARTED | Adenosine and Dexmedetomidine | 22 | |
| Dexmedetomidine | COMPLETED | Adenosine and Dexmedetomidine | 22 | |
| Dexmedetomidine | NOT COMPLETED | Adenosine and Dexmedetomidine | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Dexmedetomidine | ||
| Total, all-cause mortality | Adenosine | ||
| Total, other adverse events | Dexmedetomidine | 0 | 22 |
| Total, other adverse events | Adenosine | 0 | 22 |
| Total, serious adverse events | Dexmedetomidine | 0 | 22 |
| Total, serious adverse events | Adenosine | 0 | 22 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons5
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Dexmedetomidine vs Adenosine: Number of Participants With Sinus Pause >2.5 Sec After Termination of SVT | Trial comparisons |
| Dexmedetomidine vs Adenosine: Number of Participants With Hypotension by Non-invasive Cuff in First 10 Minutes After Medication Administration | Trial comparisons |
| Dexmedetomidine vs Adenosine: Number of Participants With Tachyarrhythmias After Medication Administration | Trial comparisons |
| Dexmedetomidine vs Adenosine: Termination of SVT | Trial comparisons |
| Dexmedetomidine vs Adenosine: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01495481
GET https://conductscience.org/api/trials/v1/NCT01495481/registered