Trial · NCT01543633
EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
NCT01543633, Not applicable, Completed, Massachusetts General Hospital; results first posted 2022-01-11
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia. Trials, record NCT01543633. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01543633
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- EEG Studies of Induction and Recovery From Propofol Induced General Anesthesia
- NCT number
- NCT01543633
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 36 participants, actual
- Lead sponsor
- Massachusetts General Hospital
- Conditions
- Brain Activity Under Sedation
- Interventions
- Propofol
- First posted
- 2012-03-05
- Last updated
- 2022-01-11
- Results first posted
- 2022-01-11
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | EEG Power in Alpha, Slow, and Delta Bands | 11 hours | We used EEG measurements to study the dynamics of loss of consciousness, auditory processing, sensation, and memory under general anesthesia induced with propofol. The EEG data in each of the three specific aims will be analyzed using spectral methods, source localization, and event-related potentials. Through spectral analysis, EEG power (in decibels) in alpha, slow, and delta bands are measured. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | EEG Power in Alpha, Slow, and Delta Bands | 11 hours | Power of alpha band (decibels) | MEDIAN |
Source ClinicalTrials.gov
Results by group3
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| EEG Power in Alpha, Slow, and Delta Bands | Active Study Arm | Alpha Band Power | 10 | 95% Confidence Interval 8 to 12 | Power of alpha band (decibels) |
| EEG Power in Alpha, Slow, and Delta Bands | Active Study Arm | Slow Band Power | 0.55 | 95% Confidence Interval 0.1 to 1 | Power of alpha band (decibels) |
| EEG Power in Alpha, Slow, and Delta Bands | Active Study Arm | Delta Band Power | 2.5 | 95% Confidence Interval 1 to 4 | Power of alpha band (decibels) |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Active Study Arm | 36 | |
| Overall Study | COMPLETED | Active Study Arm | 17 | |
| Overall Study | NOT COMPLETED | Active Study Arm | 19 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Active Study Arm | 0 | 17 |
| Total, other adverse events | Active Study Arm | 0 | 17 |
| Total, serious adverse events | Active Study Arm | 0 | 17 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| DP1OD003646 | A Systems Neuroscience Approach for the Study of General Anesthesia | BROWN, EMERY N | MASSACHUSETTS GENERAL HOSPITAL | OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH | 2007 to 2011 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01543633
GET https://conductscience.org/api/trials/v1/NCT01543633/registered