Trial · NCT01547455
Safety and Efficiency Study of Loading Dose Atorvastatin in Cardiac Surgery
NCT01547455, Not applicable, Completed, Peking Union Medical College
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety and Efficiency Study of Loading Dose Atorvastatin in Cardiac Surgery. Trials, record NCT01547455. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01547455
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety and Efficiency Study of Loading Dose Atorvastatin in Cardiac Surgery
- NCT number
- NCT01547455
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 96 participants, actual
- Lead sponsor
- Peking Union Medical College
- Conditions
- Acute Kidney Injury
- Interventions
- Atorvastatin(Lipitor), Placebo
- First posted
- 2012-03-07
- Last updated
- 2013-07-25
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | acute kidney injury | 72 hours after surgery | Proportion developing AKI using AKIN criteria(stage 1,stage 2, stage3).we plan to measure serum creatinine in baseline, ICU admission,postoperative 6h、Day 1、Day 2 and Day 3.If multiple SCr was measured in one day ,then the highest value will be recorded.Also, we measure creatinine clearance via Cock-croft-Gault formula. |
| Secondary | Change of inflammatory biomarkers | 48h after surgery | we plan to measure IL-6,IL-10,TNF-α and hsCRP at 6 time points: before surgery、after chest closure、postOp.6h、12h、24h and 48h.Compare levels of cytokines between the two arms |
| Secondary | Requirement of renal replacement therapy | participants will be followed for the duration of hospital stay , an expected average of 2 weeks | proportion need renal replacement therapy in hospital |
| Secondary | liver function | participants will be followed for the duration of hospital stay , an expected average of 2 weeks | liver dysfunction defined as transaminase\>3UNL normal level |
| Secondary | death | 30 days after discharge from hospital | |
| Secondary | MACCE events | 30 days after discharge from hospital | |
| Secondary | length of stay in intensive care unit | From admission to discharge from ICU | An average of 2 days |
| Secondary | length of stay in hospital after surgery | From surgery to discharge from hospital, an expected average of 7 days |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01547455
GET https://conductscience.org/api/trials/v1/NCT01547455/registered