Trial · NCT01563406
Hub Cleansing to Prevent Hub Infection
NCT01563406, Not applicable, Completed, Rush University Medical Center; results first posted 2016-04-18
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Hub Cleansing to Prevent Hub Infection. Trials, record NCT01563406. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT01563406
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Hub Cleansing to Prevent Hub Infection
- NCT number
- NCT01563406
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 149 participants, actual
- Lead sponsor
- Rush University Medical Center
- Conditions
- Bacteremia
- Interventions
- 15 second scrub, 5 second scrub, 3.15% chlorhexidine/70% isopropyl alcohol, 70% isopropyl alcohol
- First posted
- 2012-03-27
- Last updated
- 2016-04-18
- Results first posted
- 2016-04-18
- Limitations and caveats
* Single MICU~* Large number of eligible hubs not evaluated~* Unbalanced hub collection among study arms~* Studied hub contamination only; unable to collect catheter tips~* Did not study central-line associated bloodstream infection itself
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Central Venous Catheter Hubs With Internal Contamination | 15 months | This will be a qualitative outcome. It will be reported as "yes" or "no" for central venous catheter hub internal contamination. The number of hubs with internal contamination will be compared for the four study arms. |
| Secondary | Number of Contaminated Central Venous Catheter Tips | 10 months | This will be a qualitative measure for central venous catheter tip contamination. The results will be reported as "yes" or "no". |
| Secondary | Median Number of Microbial Colony Forming Units Per Hub Interior | 15 months | This will be a quantitative outcome. It will be reported as the median number of microbial colony forming units isolated per hub interior. The median number of microbial colony forming units isolated per hub interior will be compared for the four study arms. |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Central Venous Catheter Hubs With Internal Contamination | 15 months | 140 participants were recruited through 149 separate medical intensive care unit (MICU) admissions. Each MICU admission is treated as a separate enrollment. | contaminated hubs | NUMBER |
| SECONDARY | Number of Contaminated Central Venous Catheter Tips | 10 months | Unable to collect a sufficient number of catheter tips to analyze. Therefore, this outcome was dropped early in the study. | ||
| SECONDARY | Median Number of Microbial Colony Forming Units Per Hub Interior | 15 months | colony forming units (CFU) per hub | MEDIAN |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Central Venous Catheter Hubs With Internal Contamination | Alcohol, 15 Second Scrub | 42 | contaminated hubs | ||
| Number of Central Venous Catheter Hubs With Internal Contamination | Chlorhexidine+Alcohol, 15 Second Scrub | 18 | contaminated hubs | ||
| Number of Central Venous Catheter Hubs With Internal Contamination | Alcohol, 5 Second Scrub | 39 | contaminated hubs | ||
| Number of Central Venous Catheter Hubs With Internal Contamination | Chlorhexidine+Alcohol, 5 Second Scrub | 14 | contaminated hubs | ||
| Median Number of Microbial Colony Forming Units Per Hub Interior | Alcohol, 15 Second Scrub | 0 | Inter-Quartile Range 0 to 0 | colony forming units (CFU) per hub | |
| Median Number of Microbial Colony Forming Units Per Hub Interior | Chlorhexidine+Alcohol, 15 Second Scrub | 0 | Inter-Quartile Range 0 to 0 | colony forming units (CFU) per hub | |
| Median Number of Microbial Colony Forming Units Per Hub Interior | Alcohol, 5 Second Scrub | 0 | Inter-Quartile Range 0 to 40 | colony forming units (CFU) per hub | |
| Median Number of Microbial Colony Forming Units Per Hub Interior | Chlorhexidine+Alcohol, 5 Second Scrub | 0 | Inter-Quartile Range 0 to 0 | colony forming units (CFU) per hub |
Source ClinicalTrials.gov
Participant flow12
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Alcohol, 15 Second Scrub | 60 | |
| Overall Study | STARTED | Chlorhexidine+Alcohol, 15 Second Scrub | 30 | |
| Overall Study | STARTED | Alcohol, 5 Second Scrub | 30 | |
| Overall Study | STARTED | Chlorhexidine+Alcohol, 5 Second Scrub | 29 | |
| Overall Study | COMPLETED | Alcohol, 15 Second Scrub | 60 | |
| Overall Study | COMPLETED | Chlorhexidine+Alcohol, 15 Second Scrub | 30 | |
| Overall Study | COMPLETED | Alcohol, 5 Second Scrub | 30 | |
| Overall Study | COMPLETED | Chlorhexidine+Alcohol, 5 Second Scrub | 29 | |
| Overall Study | NOT COMPLETED | Alcohol, 15 Second Scrub | 0 | |
| Overall Study | NOT COMPLETED | Chlorhexidine+Alcohol, 15 Second Scrub | 0 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 participant flowAdverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals12
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Alcohol, 15 Second Scrub | ||
| Total, all-cause mortality | Chlorhexidine+Alcohol, 15 Second Scrub | ||
| Total, all-cause mortality | Alcohol, 5 Second Scrub | ||
| Total, all-cause mortality | Chlorhexidine+Alcohol, 5 Second Scrub | ||
| Total, other adverse events | Alcohol, 15 Second Scrub | 0 | 60 |
| Total, other adverse events | Chlorhexidine+Alcohol, 15 Second Scrub | 0 | 30 |
| Total, other adverse events | Alcohol, 5 Second Scrub | 0 | 30 |
| Total, other adverse events | Chlorhexidine+Alcohol, 5 Second Scrub | 0 | 29 |
| Total, serious adverse events | Alcohol, 15 Second Scrub | 0 | 60 |
| Total, serious adverse events | Chlorhexidine+Alcohol, 15 Second Scrub | 0 | 30 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 adverse event totalsPapers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| U54CK000161 | Chicago Prevention and Intervention Epicenter (Chicago PIE) | WEINSTEIN, ROBERT ALAN | HEKTOEN INSTITUTE FOR MEDICAL RESEARCH | National Center for Emerging and Zoonotic Infectious Diseases | 2011 to 2015 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT01563406
GET https://conductscience.org/api/trials/v1/NCT01563406/registered