Trial · NCT01626378
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 12 of 12
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change from Baseline on Addenbrooke's Cognitive Examination - Revised (ACE-R) | 52 weeks | |
| Primary | Change from Baseline on Functional Activities Questionnaire (FAQ) | 52 weeks | |
| Primary | Change from Baseline on whole brain volume (assessed by brain MRI) | 52 weeks | |
| Secondary | Change from Baseline on Unified Parkinson's Disease Rating Scale (UPDRS Parts II and III) | 52 weeks | |
| Secondary | Change from Baseline on Frontotemporal Dementia Rating Scale (FRS) | 52 weeks | |
| Secondary | Change from Baseline on Modified Alzheimer's Disease Cooperative Study - Clinical Global Impression of Change (modified ADCS-CGIC) | 52 weeks | |
| Secondary | Number of study participants who tolerate oral doses of TRx0237 as determined by safety parameter changes | 52 weeks | Safety parameters included adverse events, vital signs, methemoglobin and oxygen saturation, physical and neurological examinations, laboratory tests (hematology, serum chemistry, and urinalysis), electrocardiograms, assessment of serotonin syndrome, brain magnetic resonance imaging (MRI) and potential for suicidal behavior and thoughts |
| Other | Early effect on modified ADCS-CGIC (change from Baseline) | 8 weeks | |
| Other | Change from Baseline on the rate of atrophy in frontal and temporal lobes as well as ventricular volume (assessed by brain MRI) | 52 weeks | |
| Other | Change from Baseline on Mini-Mental Status Examination (MMSE) | 52 weeks | |
| Other | Change from Baseline on Addenbrooke's Cognitive Examination-III (ACE-III) | 52 weeks | |
| Other | Determine the effect of TRx0237 in subjects with known genetic mutations associated with bvFTD | 52 weeks |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT01626378/registered